Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6H76_RS00665 Genome accession   NZ_CP065994
Coordinates   128387..129061 (+) Length   224 a.a.
NCBI ID   WP_006532199.1    Uniprot ID   -
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 123387..134061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS00650 (I6H76_00650) pstB 124004..124762 (+) 759 WP_006532202.1 phosphate ABC transporter ATP-binding protein PstB -
  I6H76_RS00655 (I6H76_00655) phoU 124793..125446 (+) 654 WP_006532201.1 phosphate signaling complex protein PhoU -
  I6H76_RS00660 (I6H76_00660) - 125677..128220 (+) 2544 WP_006532200.1 M1 family metallopeptidase -
  I6H76_RS00665 (I6H76_00665) ciaR 128387..129061 (+) 675 WP_006532199.1 response regulator transcription factor Regulator
  I6H76_RS00670 (I6H76_00670) ciaH 129051..130379 (+) 1329 WP_006532198.1 cell wall metabolism sensor histidine kinase WalK Regulator
  I6H76_RS00675 (I6H76_00675) rpsT 130465..130716 (-) 252 WP_004231769.1 30S ribosomal protein S20 -
  I6H76_RS00680 (I6H76_00680) coaA 130792..131712 (-) 921 WP_006532197.1 type I pantothenate kinase -
  I6H76_RS00685 (I6H76_00685) - 131844..132437 (+) 594 WP_006532196.1 class I SAM-dependent methyltransferase -
  I6H76_RS00690 (I6H76_00690) deoC 132939..133604 (+) 666 WP_043878375.1 deoxyribose-phosphate aldolase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25457.16 Da        Isoelectric Point: 4.4835

>NTDB_id=516105 I6H76_RS00665 WP_006532199.1 128387..129061(+) (ciaR) [Streptococcus infantarius strain FDAARGOS_1019]
MIKILLVEDDLSLSNSIFDFLDNFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREQGITTPVLIMTA
KESLNDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNDNTLSYHELTADTSTNTTTVNGKKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=516105 I6H76_RS00665 WP_006532199.1 128387..129061(+) (ciaR) [Streptococcus infantarius strain FDAARGOS_1019]
ATGATTAAGATTTTATTAGTAGAAGATGATTTGAGTTTATCGAATTCAATCTTTGATTTTTTAGATAATTTTGCAGATGT
TATGCAAGTCTTTGATGGTGAAGAAGGGCTTTATGAGGCAGAAAGTGGTGTTTATGACCTCATTTTGCTTGATCTGATGT
TGCCAGAAAAAGATGGTTTCCAAGTTCTGAAAGAATTACGTGAACAAGGTATTACGACACCTGTCTTAATTATGACAGCC
AAAGAAAGTCTTAATGATAAAGGACACGGTTTTGAACTTGGTGCTGATGATTATTTGACAAAACCATTTTATCTTGAAGA
GTTGAAGATGCGTATTCAAGCGCTTTTGAAACGCTCTGGAAAATTCAACGATAATACTCTTTCTTACCACGAATTAACAG
CTGATACATCAACTAACACAACAACTGTTAACGGTAAAAAGGTTGAGTTACTAGGTAAAGAATTTGATTTATTGGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGATTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGCAAAAAATTAAAAGGAACAAGTTTTGCTAAAAATCTACAAACACTTC
GTAGTGTAGGGTATATTCTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.377

99.554

0.92
  ciaR Streptococcus pneumoniae Rx1

87.054

100

0.871
  ciaR Streptococcus pneumoniae D39

87.054

100

0.871
  ciaR Streptococcus pneumoniae R6

87.054

100

0.871
  ciaR Streptococcus pneumoniae TIGR4

87.054

100

0.871
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.767

100

0.393
  vicR Streptococcus mutans UA159

35.193

100

0.366