Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I6H76_RS00670 Genome accession   NZ_CP065994
Coordinates   129051..130379 (+) Length   442 a.a.
NCBI ID   WP_006532198.1    Uniprot ID   -
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 124051..135379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS00655 (I6H76_00655) phoU 124793..125446 (+) 654 WP_006532201.1 phosphate signaling complex protein PhoU -
  I6H76_RS00660 (I6H76_00660) - 125677..128220 (+) 2544 WP_006532200.1 M1 family metallopeptidase -
  I6H76_RS00665 (I6H76_00665) ciaR 128387..129061 (+) 675 WP_006532199.1 response regulator transcription factor Regulator
  I6H76_RS00670 (I6H76_00670) ciaH 129051..130379 (+) 1329 WP_006532198.1 cell wall metabolism sensor histidine kinase WalK Regulator
  I6H76_RS00675 (I6H76_00675) rpsT 130465..130716 (-) 252 WP_004231769.1 30S ribosomal protein S20 -
  I6H76_RS00680 (I6H76_00680) coaA 130792..131712 (-) 921 WP_006532197.1 type I pantothenate kinase -
  I6H76_RS00685 (I6H76_00685) - 131844..132437 (+) 594 WP_006532196.1 class I SAM-dependent methyltransferase -
  I6H76_RS00690 (I6H76_00690) deoC 132939..133604 (+) 666 WP_043878375.1 deoxyribose-phosphate aldolase -
  I6H76_RS00695 (I6H76_00695) - 133793..134857 (+) 1065 WP_006532194.1 BMP family protein -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 50126.05 Da        Isoelectric Point: 6.6262

>NTDB_id=516106 I6H76_RS00670 WP_006532198.1 129051..130379(+) (ciaH) [Streptococcus infantarius strain FDAARGOS_1019]
MLNNIHKKLSTGTFSNFFHFFIVFTGIFIIMTTIILQIMRYGLYSSVDTTLKNAADNASDYVTRTMERSDSLQSNNSFSN
SGKGKPSSNVASLSNVSVLLYDTNGKIVNVIDAFVQFGTLASSVDEDTIGEIKDEKMTTIFGQTEKYHVLTVRVYSSDYP
TIEYATFLISVSQLDEANERYVTITVSVMIIFWMISILASIYLANWMRKPILESYEKQKRFVENASHELRTPLAVLQNRL
ESLFRRPNATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIQPSIFNEIFENYNMIAEENGKTFVAHNS
ADRPIKTDRTLLKQLMTILFDNAIKYTDDDGFIEFTVKTTERQTILTVADNGPGISDADKAKIFDRFYRVDKARTRQKGG
FGLGLSLAKQIVDALKGDIQVKDNHPKGTIFEVRFNRHNFGK

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=516106 I6H76_RS00670 WP_006532198.1 129051..130379(+) (ciaH) [Streptococcus infantarius strain FDAARGOS_1019]
ATGCTGAATAACATACACAAAAAATTATCAACAGGAACGTTTTCTAATTTTTTCCATTTCTTCATTGTATTTACAGGAAT
TTTCATCATTATGACCACGATTATCTTGCAGATTATGCGTTATGGTCTATATTCTTCTGTAGATACCACTTTAAAAAATG
CAGCTGACAACGCAAGTGATTACGTCACACGAACAATGGAGCGTAGTGATTCCTTACAATCTAATAATAGTTTTAGTAAT
TCTGGAAAAGGAAAACCCAGCTCAAATGTGGCAAGTTTAAGTAATGTCAGTGTGCTATTGTACGATACAAATGGGAAAAT
CGTAAATGTAATTGATGCGTTTGTCCAGTTCGGGACATTAGCATCTAGTGTTGATGAAGACACTATTGGTGAGATTAAAG
ACGAGAAAATGACAACTATCTTTGGTCAAACCGAAAAATACCATGTTTTAACGGTTAGAGTGTATAGTAGTGACTATCCA
ACGATTGAATACGCGACTTTCTTAATCAGTGTTAGTCAGCTTGATGAGGCAAACGAACGTTATGTAACCATAACTGTTTC
AGTCATGATTATTTTCTGGATGATTTCAATTTTAGCAAGTATTTACTTGGCAAATTGGATGCGTAAACCAATTTTAGAAA
GTTATGAAAAACAAAAGCGTTTTGTTGAAAATGCTAGTCACGAATTAAGAACGCCGTTAGCGGTGCTTCAAAACCGACTT
GAAAGTCTTTTTAGACGACCGAATGCAACAATTCTTGATAACAGTGAAAGTATTGCAGCGAGTCTTGACGAAGTTCGTAA
TATGCGTATTTTAACAACCAATCTTTTGAACCTTGCTAGGCGAGATGATGGATTGAAAGTTGAATTAGAAGAAATCCAAC
CTTCAATCTTTAATGAAATTTTTGAGAATTACAACATGATTGCCGAAGAAAATGGTAAAACTTTTGTTGCTCATAATTCT
GCGGATCGTCCGATAAAAACTGATCGCACCTTGCTTAAACAATTGATGACAATCTTGTTTGATAATGCGATTAAGTACAC
TGATGACGACGGTTTTATTGAATTTACAGTTAAAACAACAGAACGCCAGACTATTCTAACCGTCGCTGATAATGGGCCGG
GTATTAGTGACGCTGATAAAGCGAAAATTTTTGATCGCTTTTATCGCGTTGATAAGGCAAGGACACGTCAAAAAGGTGGC
TTTGGACTTGGTCTATCCTTAGCTAAACAAATTGTTGATGCCTTAAAAGGTGATATTCAAGTTAAGGATAATCATCCAAA
AGGAACTATCTTTGAAGTTCGTTTTAACCGACATAATTTTGGTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.54

98.416

0.586
  ciaH Streptococcus pneumoniae Rx1

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae D39

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae R6

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae TIGR4

52.174

98.869

0.516