Detailed information NTG0515371

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: JAN99_RS04680
• Genome accession: NZ_CP065927
• Coordinates: 934326..935162 (-)
• Length: 278 a.a.
• NCBI ID: WP_136116150.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm9ST603
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 929326..940162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JAN99_RS04660 (JAN99_04655)	-	929628..930620 (-)	993	WP_136116144.1	D-lactate dehydrogenase	-
JAN99_RS04665 (JAN99_04660)	-	930635..931201 (-)	567	Protein_865	PTS sugar transporter subunit IIC	-
JAN99_RS04670 (JAN99_04665)	-	931214..932016 (+)	803	Protein_866	LysR family transcriptional regulator	-
JAN99_RS04675 (JAN99_04670)	topA	932091..934220 (-)	2130	WP_136116148.1	type I DNA topoisomerase	-
JAN99_RS04680 (JAN99_04675)	dprA	934326..935162 (-)	837	WP_136116150.1	DNA-processing protein DprA	Machinery gene
JAN99_RS04685 (JAN99_04680)	-	935227..936018 (-)	792	WP_136116153.1	ribonuclease HII	-
JAN99_RS04690 (JAN99_04685)	ylqF	936008..936856 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
JAN99_RS04695 (JAN99_04690)	-	937075..937515 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
JAN99_RS04700 (JAN99_04695)	-	937512..938162 (+)	651	WP_002984629.1	hemolysin III family protein	-
JAN99_RS04705 (JAN99_04700)	-	938279..939190 (+)	912	WP_047235287.1	diacylglycerol kinase family protein	-
JAN99_RS04710 (JAN99_04705)	-	939240..939674 (-)	435	WP_111693216.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31055.03 Da
• Isoelectric Point: 9.2565

>NTDB_id=515371 JAN99_RS04680 WP_136116150.1 934326..935162(-) (dprA) [Streptococcus pyogenes strain emm9ST603]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=515371 JAN99_RS04680 WP_136116150.1 934326..935162(-) (dprA) [Streptococcus pyogenes strain emm9ST603]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367