Detailed information NTG0514290

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: STMM8_RS09255
• Genome accession: NZ_CP065787
• Coordinates: 1769795..1771030 (+)
• Length: 411 a.a.
• NCBI ID: WP_022096467.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM8
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1764795..1776030

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM8_RS09225 (STMM8_09205)	-	1765262..1767868 (+)	2607	WP_002946816.1	YfhO family protein	-
STMM8_RS09245 (STMM8_09225)	-	1768412..1769095 (-)	684	WP_011226711.1	YoaK family protein	-
STMM8_RS09250 (STMM8_09230)	rlmH	1769111..1769590 (-)	480	WP_180473206.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
STMM8_RS09255 (STMM8_09235)	htrA	1769795..1771030 (+)	1236	WP_022096467.1	S1C family serine protease	Regulator
STMM8_RS09260 (STMM8_09240)	spo0J	1771096..1771863 (+)	768	WP_002948582.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42872.14 Da
• Isoelectric Point: 4.7061

>NTDB_id=514290 STMM8_RS09255 WP_022096467.1 1769795..1771030(+) (htrA) [Streptococcus thermophilus strain MM8]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDNGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=514290 STMM8_RS09255 WP_022096467.1 1769795..1771030(+) (htrA) [Streptococcus thermophilus strain MM8]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATAATGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAAAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCACTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (5-406)

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.596	97.567	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	57.524	100	0.577
htrA	Streptococcus mitis NCTC 12261	54.034	99.513	0.538
htrA	Streptococcus pneumoniae TIGR4	53.79	99.513	0.535
htrA	Streptococcus pneumoniae D39	53.79	99.513	0.535
htrA	Streptococcus pneumoniae Rx1	53.79	99.513	0.535
htrA	Streptococcus pneumoniae R6	53.79	99.513	0.535