Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   I6G42_RS01940 Genome accession   NZ_CP065707
Coordinates   401221..402540 (-) Length   439 a.a.
NCBI ID   WP_038804779.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_885     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 396221..407540
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G42_RS01915 (I6G42_01915) - 396923..399565 (-) 2643 WP_038804777.1 YhgE/Pip domain-containing protein -
  I6G42_RS01920 (I6G42_01920) - 399694..400236 (+) 543 WP_038804778.1 TetR/AcrR family transcriptional regulator -
  I6G42_RS01935 (I6G42_01935) comE 400472..401224 (-) 753 WP_000866081.1 competence system response regulator transcription factor ComE Regulator
  I6G42_RS01940 (I6G42_01940) comD 401221..402540 (-) 1320 WP_038804779.1 competence system sensor histidine kinase ComD Regulator
  I6G42_RS01945 (I6G42_01945) comC 402562..402687 (-) 126 WP_000799680.1 competence-stimulating peptide ComC Regulator
  I6G42_RS01955 (I6G42_01955) rlmH 402971..403450 (-) 480 WP_038804781.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6G42_RS01960 (I6G42_01960) htrA 403634..404824 (+) 1191 WP_038804782.1 S1C family serine protease Regulator
  I6G42_RS01965 (I6G42_01965) spo0J 404882..405640 (+) 759 WP_038804784.1 ParB/RepB/Spo0J family partition protein Regulator
  I6G42_RS01970 (I6G42_01970) dnaA 405864..407225 (+) 1362 WP_038804785.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51360.05 Da        Isoelectric Point: 5.3406

>NTDB_id=513270 I6G42_RS01940 WP_038804779.1 401221..402540(-) (comD) [Streptococcus oralis strain FDAARGOS_885]
MNLFGLVIAFFYVFIISKIYEWTCNATKKEKYIYSLYVFLLQLILEEIMYLLALDGYGLSKFLFPLLIFGYFVGFQKYDK
SKGVFISLLFSLLYHSSNNFISVTLSSITGDDIALEYNNYFIIFVLILTYLVIKIVISYFHLEFKYFDKEYLYSFLKKVL
YAFIFLHIVSFISDIVSTISHLNSFGSILSTIVFICLLLIFFAMNSYKVQIEKEIALKQKKFEQKHLQTYTDEIVKLYNE
IRGFRHDYAGMLVSMQMAIDSEDLQEIDRVYNEVLVKANQKLRSEKYTYFDLNNLEDSALRSLIAQSIVYARNNDVEFTL
EVKDVITRLSMDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIMLETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=513270 I6G42_RS01940 WP_038804779.1 401221..402540(-) (comD) [Streptococcus oralis strain FDAARGOS_885]
ATGAATTTATTTGGATTAGTAATAGCTTTTTTTTATGTTTTTATCATTAGTAAAATTTATGAATGGACTTGTAATGCAAC
TAAAAAAGAAAAATATATTTATAGTCTTTATGTCTTTTTACTACAATTAATATTAGAAGAAATAATGTATTTGCTAGCCT
TAGATGGTTACGGTTTGTCTAAATTTTTATTTCCTTTACTCATATTCGGTTACTTTGTTGGATTTCAGAAGTATGATAAG
TCTAAGGGAGTTTTTATAAGCCTATTATTTTCTCTCTTATATCATAGTAGTAATAACTTTATATCGGTAACTTTATCATC
TATAACAGGAGATGATATTGCATTAGAATATAATAATTATTTTATTATATTTGTACTTATTTTAACCTATTTGGTTATTA
AAATTGTCATATCTTATTTCCATTTGGAGTTTAAATATTTTGACAAAGAATATCTCTATTCTTTTTTGAAAAAAGTGCTA
TATGCATTTATCTTCTTGCATATCGTCTCTTTTATTTCAGATATCGTGAGTACTATTTCTCATTTAAATAGTTTTGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTTATAAGGTTCAAATTGAAAAAG
AGATTGCCCTAAAGCAGAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTCAAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGTATGCTTGTCAGCATGCAAATGGCAATTGACAGTGAAGATTTACAGGAAAT
TGACAGAGTTTACAATGAAGTATTAGTAAAAGCGAATCAAAAACTGCGTTCAGAAAAATATACTTACTTTGATTTGAACA
ATTTAGAAGATTCAGCTTTACGTAGTTTGATTGCTCAATCCATTGTTTATGCACGAAATAATGATGTAGAGTTTACATTG
GAAGTAAAGGATGTTATTACTAGATTGTCAATGGATTTACTTGATCTTGTTCGCATCATGAGTATTCTCTTAAACAATGC
TGTTGAAGGAGCCGCGGATAGTTACTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAGACAGTTATAGTCA
TCCAGAATTCATGTAAAATCACTATGACGCCTTCAGAGGACTTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTTTAGGGCTTAATAATGTCAAAGAGATTCTAGATAAATATGACAACATTATGTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(332-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

72.562

100

0.729
  comD Streptococcus mitis NCTC 12261

72.336

100

0.727
  comD/comD2 Streptococcus pneumoniae TIGR4

71.202

100

0.715
  comD/comD1 Streptococcus pneumoniae R6

70.748

100

0.711
  comD/comD1 Streptococcus pneumoniae Rx1

70.748

100

0.711
  comD/comD1 Streptococcus pneumoniae D39

70.748

100

0.711
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.67

85.649

0.417
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

48.396

85.194

0.412