Detailed information NTG0051326

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: Y1U_RS04015
• Genome accession: NC_017927
• Coordinates: 756697..757404 (+)
• Length: 235 a.a.
• NCBI ID: WP_014727438.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus MN-ZLW-002
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 751697..762404

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Y1U_RS03985 (Y1U_C0764)	-	751977..752165 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
Y1U_RS03990 (Y1U_C0765)	endA	752227..753108 (+)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
Y1U_RS03995 (Y1U_C0766)	-	753180..753830 (-)	651	WP_014608375.1	amino acid ABC transporter permease	-
Y1U_RS04000 (Y1U_C0767)	-	753842..754540 (-)	699	WP_014608374.1	amino acid ABC transporter permease	-
Y1U_RS04005 (Y1U_C0768)	-	754558..755391 (-)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
Y1U_RS04010 (Y1U_C0769)	-	755403..756170 (-)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
Y1U_RS04015 (Y1U_C0770)	vicR	756697..757404 (+)	708	WP_014727438.1	response regulator YycF	Regulator
Y1U_RS04020 (Y1U_C0771)	vicK	757397..758737 (+)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
Y1U_RS04025 (Y1U_C0772)	vicX	758743..759555 (+)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
Y1U_RS04030 (Y1U_C0773)	-	759615..759976 (+)	362	Protein_746	YbaN family protein	-
Y1U_RS04035 (Y1U_C0774)	-	760028..761242 (-)	1215	WP_002953123.1	aminoacyltransferase	-
Y1U_RS04040 (Y1U_C0775)	yidA	761244..762053 (-)	810	WP_011226081.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27039.94 Da
• Isoelectric Point: 5.0096

>NTDB_id=51326 Y1U_RS04015 WP_014727438.1 756697..757404(+) (vicR) [Streptococcus thermophilus MN-ZLW-002]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLHRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=51326 Y1U_RS04015 WP_014727438.1 756697..757404(+) (vicR) [Streptococcus thermophilus MN-ZLW-002]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCATCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.106	100	0.851
micA	Streptococcus pneumoniae Cp1015	79.828	99.149	0.791
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.887	98.298	0.451
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
scnR	Streptococcus mutans UA159	38.559	100	0.387