Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   I6G43_RS01045 Genome accession   NZ_CP065706
Coordinates   218541..219890 (+) Length   449 a.a.
NCBI ID   WP_038806541.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 213541..224890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS01015 (I6G43_01015) - 214080..214223 (+) 144 WP_038806548.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I6G43_RS01020 (I6G43_01020) - 214239..214397 (+) 159 WP_038806547.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I6G43_RS01025 (I6G43_01025) - 214780..214935 (+) 156 WP_000732133.1 hypothetical protein -
  I6G43_RS09285 - 214974..215186 (+) 213 WP_038806546.1 hypothetical protein -
  I6G43_RS01030 (I6G43_01030) - 215267..215455 (+) 189 WP_038806545.1 hypothetical protein -
  I6G43_RS01035 (I6G43_01035) - 215480..215686 (+) 207 WP_038806544.1 hypothetical protein -
  I6G43_RS09290 - 216014..216208 (+) 195 WP_038806543.1 hypothetical protein -
  I6G43_RS01040 (I6G43_01040) comA 216375..218528 (+) 2154 WP_038806542.1 peptide cleavage/export ABC transporter ComA Regulator
  I6G43_RS01045 (I6G43_01045) comB 218541..219890 (+) 1350 WP_038806541.1 competence pheromone export protein ComB Regulator
  I6G43_RS01050 (I6G43_01050) purC 220058..220765 (+) 708 WP_038806540.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  I6G43_RS01055 (I6G43_01055) - 220821..224546 (+) 3726 WP_038806539.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49907.92 Da        Isoelectric Point: 5.4076

>NTDB_id=513189 I6G43_RS01045 WP_038806541.1 218541..219890(+) (comB) [Streptococcus oralis strain FDAARGOS_886]
MKPEFLESAEFYHRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVQYQQGAEAVQAEAYANQLEMLKDQKKQLGYLQSSLKEGTDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTQDKIRDYKTAKSAIETGAQLDSQNAAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIT
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARLKVGDSVRFTTTKDANKELVLVSAITNIDATATKTEK
GNFFKIEAETSLTPEQAEKLRYGSEGRLTLITGKKSYLRYYWDQFLNRE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=513189 I6G43_RS01045 WP_038806541.1 218541..219890(+) (comB) [Streptococcus oralis strain FDAARGOS_886]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTACCATCGTCGTTACCATAATTTTTCCAGTCGCGTGATTTTACCTAT
GTCGCTTCTGCTCGTGTTTCTGCTAGGATTTGCAGTCTTTGCAGAGAAGGAGATTAGTTTGTCTACCAGAGCCACTGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCGACTAGCAATCAACGGATTGTGGCAAATTATCTGGAAGAGAACAAGTTG
GTCAAGCAGGGGGATCTACTCGTTCAGTACCAGCAAGGGGCGGAAGCTGTTCAAGCTGAAGCATACGCCAATCAGTTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGTTATTTGCAATCCAGTTTAAAAGAAGGGACTGATCAATTTCCAGAGGCGG
ATAAGTTTGGATACCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGAAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCCTCGCAGAATGCAGCAGCAAGTCAGAGTCAGGCCGAGATTGGCAATCTTATCAGCCAAACACAGGATAA
AATTCGAGATTACAAAACAGCTAAGTCAGCGATTGAAACAGGAGCTCAACTGGATAGTCAAAATGCAGCCTACTCATTTT
ATCAGACCTATAAAAACCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCACAAATCACC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTGCAGTATGCGGGATCTGGGGCTCAACAAGCCTACGCAACGGGACTGGA
TAGTCAACTTGAATCCCTCAAGTCTCAGCACCTAGTCAAAGTCGGCCAGGAATTAACCCTTTTGGATCAGAAAATTTTAG
AAGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGACAAGGGGAAAATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAAACCAGTGATTCTACAATGGTTGCAGAGGGGACCTTGCTAGCCCAACTCTATCCATCCTTGGAAAAAGA
AGGCAAAACTAAACTCACGGCTTATCTCAGTTCAAAAGATGTTGCAAGGCTCAAAGTAGGTGATTCTGTTCGCTTTACCA
CAACCAAGGATGCCAACAAAGAGCTCGTTCTTGTTTCTGCGATTACGAATATTGATGCGACAGCTACCAAGACTGAAAAG
GGAAATTTCTTTAAAATAGAGGCGGAGACAAGTCTGACTCCTGAACAGGCAGAAAAACTTCGCTACGGTTCAGAAGGACG
TTTGACACTAATCACAGGAAAGAAGAGTTATTTGCGCTATTATTGGGATCAATTTTTGAATAGAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

82.405

100

0.824
  comB Streptococcus pneumoniae Rx1

81.96

100

0.82
  comB Streptococcus pneumoniae D39

81.96

100

0.82
  comB Streptococcus pneumoniae R6

81.96

100

0.82
  comB Streptococcus pneumoniae TIGR4

81.737

100

0.817
  comB Streptococcus mitis NCTC 12261

80.846

100

0.808
  comB Streptococcus gordonii str. Challis substr. CH1

55.111

100

0.552