Detailed information NTG0513188

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: I6G43_RS01040
• Genome accession: NZ_CP065706
• Coordinates: 216375..218528 (+)
• Length: 717 a.a.
• NCBI ID: WP_038806542.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_886
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 211375..223528

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G43_RS01000 (I6G43_01000)	recO	211633..212403 (+)	771	WP_038806551.1	DNA repair protein RecO	-
I6G43_RS01005 (I6G43_01005)	plsX	212400..213392 (+)	993	WP_038806550.1	phosphate acyltransferase PlsX	-
I6G43_RS01010 (I6G43_01010)	-	213397..213633 (+)	237	WP_038806549.1	acyl carrier protein	-
I6G43_RS01015 (I6G43_01015)	-	214080..214223 (+)	144	WP_038806548.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I6G43_RS01020 (I6G43_01020)	-	214239..214397 (+)	159	WP_038806547.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I6G43_RS01025 (I6G43_01025)	-	214780..214935 (+)	156	WP_000732133.1	hypothetical protein	-
I6G43_RS09285	-	214974..215186 (+)	213	WP_038806546.1	hypothetical protein	-
I6G43_RS01030 (I6G43_01030)	-	215267..215455 (+)	189	WP_038806545.1	hypothetical protein	-
I6G43_RS01035 (I6G43_01035)	-	215480..215686 (+)	207	WP_038806544.1	hypothetical protein	-
I6G43_RS09290	-	216014..216208 (+)	195	WP_038806543.1	hypothetical protein	-
I6G43_RS01040 (I6G43_01040)	comA	216375..218528 (+)	2154	WP_038806542.1	peptide cleavage/export ABC transporter ComA	Regulator
I6G43_RS01045 (I6G43_01045)	comB	218541..219890 (+)	1350	WP_038806541.1	competence pheromone export protein ComB	Regulator
I6G43_RS01050 (I6G43_01050)	purC	220058..220765 (+)	708	WP_038806540.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80522.83 Da
• Isoelectric Point: 6.9424

>NTDB_id=513188 I6G43_RS01040 WP_038806542.1 216375..218528(+) (comA) [Streptococcus oralis strain FDAARGOS_886]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEELGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKKTIHIADPDPGVKLTKISRERFAQEWTGVSLFMAPSPDYKPHKEKKQGLLSFLPI
LFKQRGLITNIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMMLFFISLLALPIYTV
IIFVFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWMGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLRMM
KGDMTFNQVHYKYGYGRDVLSDINLTIPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVLVLDQGKIVEEGNHADLLARDGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=513188 I6G43_RS01040 WP_038806542.1 216375..218528(+) (comA) [Streptococcus oralis strain FDAARGOS_886]
ATGAAATTTGGGAAAAGACACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCCTTGGCTATGGTCTTTGG
CTATTATGGTAGTTATTACTCCTTGGCCCATCTACGAGAGTTGGCCAAGACGACCATGGATGGGACGACTGCTTTGGGGC
TTGTAAAGGTGGCAGAGGAGCTTGGCTTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATCTGCCTGATTTG
ACCTTTCCTTTTGTGGCCCATGTGCTCAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACAGGTCAGGATAAGAAGAC
CATCCATATCGCTGATCCAGATCCTGGTGTCAAGCTAACCAAGATTTCCCGTGAGCGATTTGCGCAAGAGTGGACAGGGG
TCAGTCTCTTTATGGCGCCATCTCCAGACTATAAACCTCATAAGGAGAAAAAACAGGGGCTCCTATCCTTCTTGCCCATC
TTATTCAAACAGCGTGGCTTAATTACCAATATCGTACTAGCGACACTCTTGGTAACCCTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACGCTGGGTATCATCTCTATTGGTTTGGTCA
TCGTCTATATTCTCCAGCAGATTTTGTCTTATGCTCAGGAGTATCTCTTACTTGTTTTGGGGCAACGCCTGTCAATTGAT
GTGATTTTGTCTTATATCAAGCATGTTTTTCACCTGCCAATGTCCTTTTTCGCGACACGCAGGACAGGAGAAATCGTATC
TCGTTTTACAGATGCCAATAGTATCATTGACGCGCTAGCGTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATTTCGCTTGTCTTGTTTTCACAAAATATGATGCTCTTTTTCATTAGTCTGCTTGCCCTTCCCATCTATACAGTG
ATTATCTTTGTCTTTATGAAACCTTTTGAAAAGATGAATCGGGATACAATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGATATCAACGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCGCGCTATCAAAAGATTGACAAGGAAT
TTGTGGCTTATCTGAAAAAATCTTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCACTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCTGTTCTCTGGATGGGAGCTATTCTCGTCATGGATGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAACACCCTGCTCGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTGAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTCGAAGATTTGAGGATGATG
AAAGGAGATATGACTTTCAATCAGGTTCACTACAAGTATGGCTATGGTCGAGATGTTTTGTCGGATATCAATTTGACCAT
TCCGCAAGGTTCTAAAGTGGCTTTCGTGGGAATTTCAGGATCAGGCAAGACAACTTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGGGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGACAAAAAGGCTTTGCGCCAGTACATT
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGATATCTTACGGGCGGTTGAGTTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCACTGAATTATCAGACAG
AATTAACTTCGGATGGGGCTGGAATTTCAGGTGGACAACGTCAGCGAATCGCTCTGGCGCGAGCTCTTTTAACGGATGCG
CCTGTCTTGATATTGGATGAGGCGACCAGCAGTCTGGATATCTTGACAGAGAAGCGGATTGTGGATAATCTCATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCACCGCTTGACCATTGCTGAGCGGACAGAGAAGGTTCTTGTCTTGGATCAGGGTA
AGATTGTCGAAGAAGGCAATCATGCTGATTTGCTGGCTCGAGATGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	95.258	100	0.953
comA	Streptococcus pneumoniae Rx1	94.84	100	0.948
comA	Streptococcus pneumoniae D39	94.84	100	0.948
comA	Streptococcus pneumoniae R6	94.84	100	0.948
comA	Streptococcus mitis SK321	94.561	100	0.946
comA	Streptococcus pneumoniae TIGR4	94.421	100	0.944
comA	Streptococcus gordonii str. Challis substr. CH1	80.893	100	0.809
comA/nlmT	Streptococcus mutans UA159	64.714	100	0.647