Detailed information NTG0511302

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ST4147_RS01565
• Genome accession: NZ_CP065504
• Coordinates: 281188..282087 (+)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4147
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 276188..287087

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4147_RS01545 (ST4147_01530)	trkA	277324..278673 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
ST4147_RS01550 (ST4147_01535)	-	278962..279471 (+)	510	WP_011680717.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
ST4147_RS01555 (ST4147_01540)	-	279783..280340 (+)	558	WP_002949523.1	ECF transporter S component	-
ST4147_RS01560 (ST4147_01545)	-	280343..280993 (+)	651	WP_011226853.1	phosphatase PAP2 family protein	-
ST4147_RS01565 (ST4147_01550)	comR	281188..282087 (+)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
ST4147_RS01570 (ST4147_01555)	-	282326..283504 (+)	1179	Protein_256	ABC transporter transmembrane domain-containing protein	-
ST4147_RS01575 (ST4147_01570)	-	283790..284358 (+)	569	Protein_257	ATP-binding cassette domain-containing protein	-
ST4147_RS01580 (ST4147_01575)	-	284466..284777 (+)	312	WP_011226857.1	DUF805 domain-containing protein	-
ST4147_RS01585	-	284745..285029 (-)	285	WP_231108755.1	hypothetical protein	-
ST4147_RS01590	-	285269..285571 (-)	303	WP_011226859.1	hypothetical protein	-
ST4147_RS01595	-	285795..286166 (-)	372	WP_231108754.1	hypothetical protein	-
ST4147_RS01600 (ST4147_01585)	-	286571..287086 (+)	516	WP_011226861.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=511302 ST4147_RS01565 WP_011226854.1 281188..282087(+) (comR) [Streptococcus thermophilus strain 4147]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=511302 ST4147_RS01565 WP_011226854.1 281188..282087(+) (comR) [Streptococcus thermophilus strain 4147]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421