Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SPAF_RS03710 Genome accession   NC_017905
Coordinates   720085..722331 (+) Length   748 a.a.
NCBI ID   WP_014713071.1    Uniprot ID   I1ZKY7
Organism   Streptococcus parasanguinis FW213     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 715085..727331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPAF_RS03690 (Spaf_0701) - 715282..716028 (-) 747 WP_003017755.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  SPAF_RS03695 (Spaf_0702) - 716109..718448 (-) 2340 WP_041826264.1 cation-translocating P-type ATPase -
  SPAF_RS03700 (Spaf_0703) - 718623..719369 (+) 747 WP_014713069.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SPAF_RS03705 (Spaf_0704) comEA/celA/cilE 719436..720104 (+) 669 WP_014713070.1 helix-hairpin-helix domain-containing protein Machinery gene
  SPAF_RS03710 (Spaf_0705) comEC/celB 720085..722331 (+) 2247 WP_014713071.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SPAF_RS03715 (Spaf_0706) - 722407..723009 (+) 603 WP_014713072.1 DUF805 domain-containing protein -
  SPAF_RS03720 (Spaf_0707) holA 723033..724067 (+) 1035 WP_014713073.1 DNA polymerase III subunit delta -
  SPAF_RS03725 (Spaf_0708) sodA 724155..724760 (+) 606 WP_003017685.1 superoxide dismutase SodA -
  SPAF_RS03730 (Spaf_0709) - 724972..726441 (+) 1470 WP_014713074.1 helicase HerA-like domain-containing protein -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 85895.32 Da        Isoelectric Point: 9.2753

>NTDB_id=51129 SPAF_RS03710 WP_014713071.1 720085..722331(+) (comEC/celB) [Streptococcus parasanguinis FW213]
MLSRWIKDLPFSLVHLAFLLLWLYFSVYQPSWLSISGLVVVGILAVHHYKGDRSSLLGLALATFCFAAFFVFHRIQDHPV
QAESQPPSHLRLIPDTIKINGDALSFRAKNQGRTYQVFYTLKSEKEKQQWQSQTHLLELTYKGVIEEPEGQRNFRGFDYR
SYLQTQGIHYQIKIEAIQSALPIQTWNVFDWLSQWRRQAIVWSKEHYPQPMNQYMTGLLFGYLDTDFEEMDQLYTSLGII
HLFALSGMQVGFFINGIRKALLRLGILQETVDIWMVPISLVYAGLTGFSVSVVRSLLQKILSQKSIRGMENMAMTLMLLM
LLMPKFLLTAGGVLSCAYAFILTLVDTSSYSGLKKLLVESFWISLGILPLLTYYFSVFQPWSLPLTFLFSFLFDLVLLPG
LTVLFILSILKPLTIFNSFFLLIEECIRWISKLTSLPLVFGQPTGPALIALFLLLRILYDLRKQKKRRFLLIGMILIIFC
WTKHPLENEITMVDIGQGDSIFLRDWKGRTILIDVGGRVTFKSGDKWQERSQSANADQTLIPYLKSRGVGKLDALVLTHT
DQDHMGDMLEVARQIPVKKVYVSPGSLTSSKFQEKLKQLHSPIKVVQRGDRLPIFDHDLEVLSPDEVGDGKNDDSIVLYG
QFYQKRFLFTGDLEEAGEKKLLENYPQLQVDVLKVGHHGSKGSSSDVFLDQVHPQLALISVGKKNRYQHPHKELLDRLEE
RSISYLRTDERGAIRLIGWDHWRVETVR

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=51129 SPAF_RS03710 WP_014713071.1 720085..722331(+) (comEC/celB) [Streptococcus parasanguinis FW213]
ATGCTTTCACGGTGGATTAAAGACCTTCCTTTTTCCCTTGTCCATCTCGCCTTTTTACTCCTATGGCTGTATTTTAGTGT
TTATCAACCATCTTGGCTTTCGATCAGCGGTCTAGTAGTAGTGGGAATTTTAGCGGTTCATCATTATAAAGGGGATCGTT
CTAGTTTGCTAGGTCTTGCTTTAGCAACCTTTTGTTTTGCGGCCTTCTTTGTCTTTCATCGAATACAGGATCATCCAGTA
CAAGCAGAAAGTCAGCCCCCATCCCACTTACGCCTGATTCCAGATACTATCAAGATCAATGGGGACGCCCTGTCTTTTCG
TGCTAAAAATCAGGGAAGGACCTACCAAGTCTTCTACACTTTAAAATCAGAAAAAGAAAAACAGCAGTGGCAAAGTCAAA
CCCACTTGCTGGAGTTGACATATAAAGGTGTTATAGAGGAACCAGAAGGACAACGAAATTTTAGAGGATTTGACTACCGG
TCTTATTTGCAAACACAGGGGATTCACTATCAAATAAAAATTGAAGCGATCCAATCCGCTCTTCCCATCCAGACGTGGAA
TGTTTTTGACTGGCTATCTCAATGGAGGCGCCAAGCCATTGTTTGGAGCAAGGAGCACTATCCGCAGCCAATGAACCAGT
ATATGACCGGCCTTCTTTTTGGCTATTTAGATACGGATTTTGAAGAGATGGATCAGCTTTACACGAGTTTAGGAATCATC
CATTTATTCGCCTTATCGGGGATGCAGGTCGGCTTTTTCATCAATGGGATCCGGAAAGCTCTCTTACGTCTAGGAATCTT
GCAAGAGACAGTCGATATCTGGATGGTTCCAATTTCTTTGGTGTATGCTGGCTTGACAGGTTTTTCAGTTTCAGTGGTTC
GCAGTCTCTTGCAGAAGATTCTCTCTCAAAAGAGCATCCGAGGGATGGAGAATATGGCGATGACCTTGATGCTCTTAATG
CTGCTCATGCCCAAGTTTCTCCTGACAGCTGGAGGGGTCTTGAGTTGTGCCTATGCCTTTATTTTGACCTTGGTAGATAC
CAGTTCTTATTCAGGACTTAAAAAGCTACTAGTGGAAAGTTTCTGGATTAGCCTGGGGATTTTGCCCCTTTTGACCTATT
ACTTTAGTGTCTTTCAACCGTGGTCACTCCCTTTAACCTTCCTCTTTTCTTTCTTATTTGACCTTGTCCTTCTTCCAGGT
TTAACGGTGCTATTTATCTTATCGATTCTAAAGCCCCTTACAATTTTTAACAGTTTCTTTCTTCTCATAGAGGAGTGTAT
TCGTTGGATTTCAAAGCTCACGTCCTTACCTTTGGTATTTGGTCAGCCGACGGGACCAGCTCTGATTGCTCTCTTTCTTC
TTTTAAGGATCTTATATGATCTTCGAAAGCAAAAAAAACGTCGTTTCCTGTTAATAGGTATGATTCTAATCATCTTTTGT
TGGACCAAGCATCCTTTAGAAAATGAGATCACCATGGTGGATATCGGTCAAGGAGATAGTATCTTTTTACGCGATTGGAA
AGGAAGAACCATATTGATTGATGTCGGAGGACGCGTCACTTTTAAAAGTGGAGACAAGTGGCAAGAGCGCAGTCAATCTG
CCAATGCGGATCAAACCCTGATTCCCTATCTCAAGAGTCGAGGTGTTGGAAAACTCGATGCTTTGGTCTTGACTCATACA
GACCAGGACCATATGGGCGATATGTTAGAGGTTGCAAGACAAATCCCGGTTAAAAAAGTGTATGTCAGTCCAGGAAGTCT
AACCAGTTCGAAATTTCAAGAGAAATTGAAACAGCTTCATAGTCCGATTAAAGTAGTCCAGAGAGGGGATCGTCTTCCTA
TTTTTGATCATGATCTAGAAGTCTTATCCCCTGATGAAGTGGGGGATGGTAAAAATGATGATTCGATTGTCCTCTATGGG
CAGTTCTATCAGAAACGATTTTTGTTCACGGGTGATCTGGAAGAAGCTGGAGAGAAAAAACTTTTGGAAAACTATCCACA
ATTACAAGTGGATGTCTTGAAAGTAGGCCACCACGGTTCTAAAGGTTCCTCTAGTGATGTGTTTTTGGATCAGGTACATC
CTCAATTGGCCTTGATCTCTGTTGGCAAGAAAAATCGCTACCAGCATCCCCATAAAGAATTACTCGATCGATTAGAGGAA
CGATCTATTTCTTATCTTCGTACCGATGAAAGAGGAGCGATTCGCTTGATTGGATGGGACCATTGGAGGGTGGAAACGGT
CCGCTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(496-700)

Competence protein (Competence)

(218-462)

Domain of unknown function (DUF4131) (DUF4131)

(30-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I1ZKY7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

52.878

99.866

0.528
  comEC/celB Streptococcus mitis NCTC 12261

52.011

99.733

0.519
  comEC/celB Streptococcus pneumoniae TIGR4

51.941

99.866

0.519
  comEC/celB Streptococcus pneumoniae Rx1

51.673

99.866

0.516
  comEC/celB Streptococcus pneumoniae D39

51.673

99.866

0.516
  comEC/celB Streptococcus pneumoniae R6

51.673

99.866

0.516
  comEC Lactococcus lactis subsp. cremoris KW2

47.263

100

0.473

Multiple sequence alignment