Detailed information NTG0511238

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STT55_RS01475
• Genome accession: NZ_CP065502
• Coordinates: 266156..267055 (+)
• Length: 299 a.a.
• NCBI ID: WP_002946143.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST55
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 261156..272055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT55_RS01455 (STT55_01445)	trkA	262293..263642 (-)	1350	WP_084829332.1	Trk system potassium transporter TrkA	-
STT55_RS01460 (STT55_01450)	-	263931..264440 (+)	510	WP_022096566.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
STT55_RS01465 (STT55_01455)	-	264751..265308 (+)	558	WP_173940568.1	ECF transporter S component	-
STT55_RS01470 (STT55_01460)	-	265311..265961 (+)	651	WP_022096567.1	phosphatase PAP2 family protein	-
STT55_RS01475 (STT55_01465)	comR	266156..267055 (+)	900	WP_002946143.1	helix-turn-helix domain-containing protein	Regulator
STT55_RS01480 (STT55_01470)	-	267293..268471 (+)	1179	Protein_238	ABC transporter transmembrane domain-containing protein	-
STT55_RS01485	comA	268493..268702 (+)	210	WP_002946147.1	hypothetical protein	Regulator
STT55_RS01490 (STT55_01485)	-	268757..269325 (+)	569	Protein_240	ATP-binding cassette domain-containing protein	-
STT55_RS01495 (STT55_01490)	-	269433..269744 (+)	312	WP_173940567.1	DUF805 domain-containing protein	-
STT55_RS01500	-	269712..269996 (-)	285	WP_232085805.1	hypothetical protein	-
STT55_RS01505	-	269965..270312 (-)	348	WP_232089310.1	DUF4173 domain-containing protein	-
STT55_RS01510	-	270237..271133 (-)	897	WP_224103642.1	urease cluster protein	-
STT55_RS01515 (STT55_01500)	-	271538..272053 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35303.77 Da
• Isoelectric Point: 5.1073

>NTDB_id=511238 STT55_RS01475 WP_002946143.1 266156..267055(+) (comR) [Streptococcus thermophilus strain ST55]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=511238 STT55_RS01475 WP_002946143.1 266156..267055(+) (comR) [Streptococcus thermophilus strain ST55]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	99.666	100	0.997
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418