Detailed information NTG0511199

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: STT128_RS05480
• Genome accession: NZ_CP065500
• Coordinates: 1047274..1047981 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST128
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1042274..1052981

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT128_RS05460 (STT128_05540)	-	1043290..1044539 (-)	1250	Protein_1020	ISL3 family transposase	-
STT128_RS05465 (STT128_05545)	-	1044702..1045063 (-)	362	Protein_1021	YbaN family protein	-
STT128_RS05470 (STT128_05550)	vicX	1045123..1045935 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
STT128_RS05475 (STT128_05555)	vicK	1045941..1047281 (-)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
STT128_RS05480 (STT128_05560)	vicR	1047274..1047981 (-)	708	WP_011681206.1	response regulator YycF	Regulator
STT128_RS05485 (STT128_05565)	-	1048508..1049275 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
STT128_RS05490 (STT128_05570)	-	1049287..1050120 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
STT128_RS05495 (STT128_05575)	-	1050138..1050836 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STT128_RS05500 (STT128_05580)	-	1050848..1051498 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
STT128_RS05505 (STT128_05585)	endA	1051570..1052451 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
STT128_RS05510 (STT128_05590)	-	1052513..1052701 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=511199 STT128_RS05480 WP_011681206.1 1047274..1047981(-) (vicR) [Streptococcus thermophilus strain ST128]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=511199 STT128_RS05480 WP_011681206.1 1047274..1047981(-) (vicR) [Streptococcus thermophilus strain ST128]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387