Detailed information NTG0511200

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STT128_RS05505
• Genome accession: NZ_CP065500
• Coordinates: 1051570..1052451 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST128
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1046570..1057451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT128_RS05480 (STT128_05560)	vicR	1047274..1047981 (-)	708	WP_011681206.1	response regulator YycF	Regulator
STT128_RS05485 (STT128_05565)	-	1048508..1049275 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
STT128_RS05490 (STT128_05570)	-	1049287..1050120 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
STT128_RS05495 (STT128_05575)	-	1050138..1050836 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STT128_RS05500 (STT128_05580)	-	1050848..1051498 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
STT128_RS05505 (STT128_05585)	endA	1051570..1052451 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
STT128_RS05510 (STT128_05590)	-	1052513..1052701 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STT128_RS05515 (STT128_05595)	murA	1052703..1053974 (-)	1272	WP_095559391.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STT128_RS05520 (STT128_05600)	-	1054044..1054280 (-)	237	WP_347230021.1	DUF1146 family protein	-
STT128_RS05525 (STT128_05605)	galE	1054468..1055481 (-)	1014	WP_180482601.1	UDP-glucose 4-epimerase GalE	-
STT128_RS05530 (STT128_05610)	-	1055496..1055849 (-)	354	WP_347230022.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=511200 STT128_RS05505 WP_011681210.1 1051570..1052451(-) (endA) [Streptococcus thermophilus strain ST128]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=511200 STT128_RS05505 WP_011681210.1 1051570..1052451(-) (endA) [Streptococcus thermophilus strain ST128]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594