Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ST4067_RS07160 Genome accession   NZ_CP065496
Coordinates   1376437..1377132 (-) Length   231 a.a.
NCBI ID   WP_082309090.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4067     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1371437..1382132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4067_RS07145 (ST4067_07175) - 1372248..1372793 (-) 546 WP_022096992.1 GNAT family N-acetyltransferase -
  ST4067_RS07150 (ST4067_07180) - 1372859..1374121 (-) 1263 WP_022096991.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ST4067_RS07155 (ST4067_07185) - 1374207..1376447 (-) 2241 WP_263604460.1 DNA internalization-related competence protein ComEC/Rec2 -
  ST4067_RS07160 (ST4067_07190) comEA 1376437..1377132 (-) 696 WP_082309090.1 helix-hairpin-helix domain-containing protein Machinery gene
  ST4067_RS07165 (ST4067_07195) - 1377241..1377996 (-) 756 WP_002948862.1 lysophospholipid acyltransferase family protein -
  ST4067_RS09730 - 1378194..1378739 (+) 546 WP_263604461.1 polysaccharide deacetylase family protein -
  ST4067_RS07175 - 1378655..1379071 (+) 417 WP_311316677.1 hypothetical protein -
  ST4067_RS07180 (ST4067_07205) - 1379121..1379885 (+) 765 WP_084826100.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ST4067_RS07185 (ST4067_07210) - 1379889..1380158 (+) 270 WP_002948849.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24514.46 Da        Isoelectric Point: 4.6300

>NTDB_id=511092 ST4067_RS07160 WP_082309090.1 1376437..1377132(-) (comEA) [Streptococcus thermophilus strain 4067]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=511092 ST4067_RS07160 WP_082309090.1 1376437..1377132(-) (comEA) [Streptococcus thermophilus strain 4067]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

99.134

100

0.991
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372