Detailed information NTG0511023

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: STCNRZ385_RS05440
• Genome accession: NZ_CP065495
• Coordinates: 1041893..1042600 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ385
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1036893..1047600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ385_RS05415 (STCNRZ385_05420)	yidA	1037244..1038053 (+)	810	WP_011226081.1	sugar-phosphatase	-
STCNRZ385_RS05420 (STCNRZ385_05425)	-	1038055..1039269 (+)	1215	WP_004197368.1	aminoacyltransferase	-
STCNRZ385_RS05425 (STCNRZ385_05430)	-	1039321..1039682 (-)	362	Protein_1007	YbaN family protein	-
STCNRZ385_RS05430 (STCNRZ385_05435)	vicX	1039742..1040554 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
STCNRZ385_RS05435 (STCNRZ385_05440)	vicK	1040560..1041900 (-)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
STCNRZ385_RS05440 (STCNRZ385_05445)	vicR	1041893..1042600 (-)	708	WP_011681206.1	response regulator YycF	Regulator
STCNRZ385_RS05445 (STCNRZ385_05450)	-	1043127..1043894 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
STCNRZ385_RS05450 (STCNRZ385_05455)	-	1043906..1044739 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
STCNRZ385_RS05455 (STCNRZ385_05460)	-	1044757..1045455 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STCNRZ385_RS05460 (STCNRZ385_05465)	-	1045467..1046117 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
STCNRZ385_RS05465 (STCNRZ385_05470)	endA	1046189..1047070 (-)	882	WP_180483255.1	DNA/RNA non-specific endonuclease	Machinery gene
STCNRZ385_RS05470 (STCNRZ385_05475)	-	1047132..1047320 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=511023 STCNRZ385_RS05440 WP_011681206.1 1041893..1042600(-) (vicR) [Streptococcus thermophilus strain CNRZ385]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=511023 STCNRZ385_RS05440 WP_011681206.1 1041893..1042600(-) (vicR) [Streptococcus thermophilus strain CNRZ385]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387