Detailed information NTG0511024

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STCNRZ385_RS05465
• Genome accession: NZ_CP065495
• Coordinates: 1046189..1047070 (-)
• Length: 293 a.a.
• NCBI ID: WP_180483255.1
• Uniprot ID: A0AAU9H7G4
• Organism: Streptococcus thermophilus strain CNRZ385
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1041189..1052070

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ385_RS05440 (STCNRZ385_05445)	vicR	1041893..1042600 (-)	708	WP_011681206.1	response regulator YycF	Regulator
STCNRZ385_RS05445 (STCNRZ385_05450)	-	1043127..1043894 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
STCNRZ385_RS05450 (STCNRZ385_05455)	-	1043906..1044739 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
STCNRZ385_RS05455 (STCNRZ385_05460)	-	1044757..1045455 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STCNRZ385_RS05460 (STCNRZ385_05465)	-	1045467..1046117 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
STCNRZ385_RS05465 (STCNRZ385_05470)	endA	1046189..1047070 (-)	882	WP_180483255.1	DNA/RNA non-specific endonuclease	Machinery gene
STCNRZ385_RS05470 (STCNRZ385_05475)	-	1047132..1047320 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STCNRZ385_RS05475 (STCNRZ385_05480)	murA	1047322..1048593 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ385_RS05480 (STCNRZ385_05485)	-	1048663..1048899 (-)	237	WP_002946959.1	DUF1146 family protein	-
STCNRZ385_RS05485 (STCNRZ385_05490)	galE	1049087..1050100 (-)	1014	WP_014727437.1	UDP-glucose 4-epimerase GalE	-
STCNRZ385_RS05490 (STCNRZ385_05495)	-	1050115..1050618 (-)	504	WP_224102963.1	DUF4832 domain-containing protein	-
STCNRZ385_RS05495 (STCNRZ385_05500)	-	1050608..1051060 (-)	453	WP_011681214.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31816.52 Da
• Isoelectric Point: 10.0477

>NTDB_id=511024 STCNRZ385_RS05465 WP_180483255.1 1046189..1047070(-) (endA) [Streptococcus thermophilus strain CNRZ385]
MVERKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLLRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=511024 STCNRZ385_RS05465 WP_180483255.1 1046189..1047070(-) (endA) [Streptococcus thermophilus strain CNRZ385]
ATGGTAGAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTAATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGACGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTATTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.385	81.57	0.59
endA	Streptococcus pneumoniae D39	72.385	81.57	0.59
endA	Streptococcus pneumoniae R6	72.385	81.57	0.59
endA	Streptococcus pneumoniae TIGR4	72.385	81.57	0.59