Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ST4021_RS07365 Genome accession   NZ_CP065493
Coordinates   1432799..1433494 (-) Length   231 a.a.
NCBI ID   WP_011681496.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4021     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1427799..1438494
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4021_RS07350 (ST4021_07390) - 1428610..1429155 (-) 546 WP_014608611.1 GNAT family N-acetyltransferase -
  ST4021_RS07355 (ST4021_07395) - 1429221..1430483 (-) 1263 WP_014608612.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ST4021_RS07360 (ST4021_07400) - 1430569..1432809 (-) 2241 WP_046206493.1 DNA internalization-related competence protein ComEC/Rec2 -
  ST4021_RS07365 (ST4021_07405) comEA 1432799..1433494 (-) 696 WP_011681496.1 helix-hairpin-helix domain-containing protein Machinery gene
  ST4021_RS07370 (ST4021_07410) - 1433602..1434357 (-) 756 WP_011681497.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ST4021_RS07375 (ST4021_07415) - 1434557..1435423 (+) 867 WP_014621873.1 polysaccharide deacetylase family protein -
  ST4021_RS07380 (ST4021_07420) - 1435473..1436237 (+) 765 WP_011681498.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ST4021_RS07385 (ST4021_07425) - 1436241..1436510 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24470.41 Da        Isoelectric Point: 4.6300

>NTDB_id=510973 ST4021_RS07365 WP_011681496.1 1432799..1433494(-) (comEA) [Streptococcus thermophilus strain 4021]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRAEDVIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=510973 ST4021_RS07365 WP_011681496.1 1432799..1433494(-) (comEA) [Streptococcus thermophilus strain 4021]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGGCAGAGGATGTCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

100

100

1
  comEA/celA/cilE Streptococcus mitis SK321

40.611

99.134

0.403
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.719

98.701

0.372