Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ST4145_RS07210 Genome accession   NZ_CP065492
Coordinates   1406612..1407307 (-) Length   231 a.a.
NCBI ID   WP_024010042.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4145     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1401612..1412307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4145_RS07195 (ST4145_07135) - 1402423..1402968 (-) 546 WP_014608611.1 GNAT family N-acetyltransferase -
  ST4145_RS07200 (ST4145_07140) - 1403034..1404296 (-) 1263 WP_014608612.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ST4145_RS07205 (ST4145_07145) - 1404382..1406622 (-) 2241 WP_024010041.1 DNA internalization-related competence protein ComEC/Rec2 -
  ST4145_RS07210 (ST4145_07150) comEA 1406612..1407307 (-) 696 WP_024010042.1 helix-hairpin-helix domain-containing protein Machinery gene
  ST4145_RS07215 (ST4145_07155) - 1407415..1408170 (-) 756 WP_011681497.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ST4145_RS07220 - 1408370..1408903 (+) 534 WP_082245820.1 polysaccharide deacetylase family protein -
  ST4145_RS07225 - 1409012..1409161 (+) 150 WP_014608616.1 polysaccharide deacetylase -
  ST4145_RS07230 (ST4145_07165) - 1409211..1409975 (+) 765 WP_014608617.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  ST4145_RS07235 (ST4145_07170) - 1409979..1410248 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24469.47 Da        Isoelectric Point: 4.8189

>NTDB_id=510912 ST4145_RS07210 WP_024010042.1 1406612..1407307(-) (comEA) [Streptococcus thermophilus strain 4145]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMKAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRAEDVIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=510912 ST4145_RS07210 WP_024010042.1 1406612..1407307(-) (comEA) [Streptococcus thermophilus strain 4145]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGAAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGGCAGAGGATGTCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

99.567

100

0.996
  comEA/celA/cilE Streptococcus mitis SK321

39.912

98.701

0.394
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae D39

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus pneumoniae R6

39.035

98.701

0.385
  comEA/celA/cilE Streptococcus mitis NCTC 12261

38.158

98.701

0.377