Detailed information NTG0510807

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: STCNRZ1575_RS08920
• Genome accession: NZ_CP065490
• Coordinates: 1708862..1709962 (-)
• Length: 366 a.a.
• NCBI ID: WP_120764773.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ1575
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1703862..1714962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1575_RS08875	-	1704187..1704462 (-)	276	WP_011681681.1	hypothetical protein	-
STCNRZ1575_RS08880 (STCNRZ1575_08835)	-	1704474..1704671 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STCNRZ1575_RS08885 (STCNRZ1575_08840)	-	1704920..1706113 (-)	1194	WP_014608740.1	acetate kinase	-
STCNRZ1575_RS08890 (STCNRZ1575_08845)	comYH	1706169..1707125 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STCNRZ1575_RS08895 (STCNRZ1575_08850)	comGG	1707170..1707487 (-)	318	WP_082309152.1	competence type IV pilus minor pilin ComGG	-
STCNRZ1575_RS08900 (STCNRZ1575_08855)	comYF	1707465..1707902 (-)	438	WP_082309153.1	competence type IV pilus minor pilin ComGF	Machinery gene
STCNRZ1575_RS08905 (STCNRZ1575_08860)	comGE	1707886..1708179 (-)	294	WP_082309154.1	competence type IV pilus minor pilin ComGE	-
STCNRZ1575_RS08910 (STCNRZ1575_08865)	comGD	1708151..1708579 (-)	429	WP_253269448.1	competence type IV pilus minor pilin ComGD	-
STCNRZ1575_RS08915 (STCNRZ1575_08870)	comYC	1708539..1708865 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STCNRZ1575_RS08920 (STCNRZ1575_08875)	comYB	1708862..1709962 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
STCNRZ1575_RS08925 (STCNRZ1575_08880)	comYA	1709844..1710785 (-)	942	WP_084829888.1	competence type IV pilus ATPase ComGA	Machinery gene
STCNRZ1575_RS08930 (STCNRZ1575_08885)	-	1710866..1711228 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41876.03 Da
• Isoelectric Point: 10.1377

>NTDB_id=510807 STCNRZ1575_RS08920 WP_120764773.1 1708862..1709962(-) (comYB) [Streptococcus thermophilus strain CNRZ1575]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=510807 STCNRZ1575_RS08920 WP_120764773.1 1708862..1709962(-) (comYB) [Streptococcus thermophilus strain CNRZ1575]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCCCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413