Detailed information NTG0510781

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: STCNRZ1575_RS04860
• Genome accession: NZ_CP065490
• Coordinates: 908937..909662 (+)
• Length: 241 a.a.
• NCBI ID: WP_101415611.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ1575
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 903937..914662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1575_RS04825 (STCNRZ1575_04765)	-	904030..904212 (+)	183	WP_006531883.1	Blp family class II bacteriocin	-
STCNRZ1575_RS04830 (STCNRZ1575_04770)	-	904829..905059 (+)	231	WP_043878356.1	bacteriocin	-
STCNRZ1575_RS04835 (STCNRZ1575_04775)	-	905148..905459 (+)	312	WP_003066586.1	hypothetical protein	-
STCNRZ1575_RS04840 (STCNRZ1575_04780)	-	905673..905765 (+)	93	Protein_883	Blp family class II bacteriocin	-
STCNRZ1575_RS04845 (STCNRZ1575_04785)	-	905823..906227 (+)	405	WP_015695682.1	hypothetical protein	-
STCNRZ1575_RS04850 (STCNRZ1575_04790)	-	906408..907454 (+)	1047	WP_095559358.1	thioredoxin fold domain-containing protein	-
STCNRZ1575_RS04855 (STCNRZ1575_04795)	-	907986..908750 (+)	765	WP_232086163.1	DUF6261 family protein	-
STCNRZ1575_RS04860 (STCNRZ1575_04800)	comE/comE1	908937..909662 (+)	726	WP_101415611.1	response regulator transcription factor	Regulator
STCNRZ1575_RS04865 (STCNRZ1575_04805)	-	909675..910994 (+)	1320	WP_095559360.1	GHKL domain-containing protein	-
STCNRZ1575_RS04870 (STCNRZ1575_04810)	-	911015..911164 (-)	150	WP_006531893.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
STCNRZ1575_RS04880 (STCNRZ1575_04820)	-	911691..912275 (+)	585	WP_232086162.1	hypothetical protein	-
STCNRZ1575_RS04885 (STCNRZ1575_04825)	csm6	912290..913381 (+)	1092	WP_101415612.1	type III-A CRISPR-associated CARF protein Csm6	-
STCNRZ1575_RS04890 (STCNRZ1575_04830)	pyrF	913582..914277 (+)	696	WP_011681116.1	orotidine-5'-phosphate decarboxylase	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 28093.06 Da
• Isoelectric Point: 5.0805

>NTDB_id=510781 STCNRZ1575_RS04860 WP_101415611.1 908937..909662(+) (comE/comE1) [Streptococcus thermophilus strain CNRZ1575]
MDIFVLEDDIPQQFRMERAINLVMESNNWHYRYLEISSNPDEIIAVAGNGEHQIFFLDLEIKGEEQQGIDVAKAIREKNS
TAIIVFVTTHSEFMLLTYQSLVGAIDFIDKGLNEEAFNERLFVCLKEAVKRQEGNFGEHSYLFHTPQAKVRVAYDDILFF
ETSPAPHRIILHTKNERTEFYATIAEVAKSDERLFRCHRSFVVNVDNIARFDMRYKLIYFEMGETCPVARAKVKLLQEKI
E

Nucleotide

• Length: 726 bp

>NTDB_id=510781 STCNRZ1575_RS04860 WP_101415611.1 908937..909662(+) (comE/comE1) [Streptococcus thermophilus strain CNRZ1575]
GTGGATATTTTTGTACTCGAAGATGATATTCCCCAACAATTCCGAATGGAGCGTGCTATTAATCTTGTGATGGAATCAAA
TAACTGGCATTATCGGTATTTGGAGATTTCATCTAATCCTGATGAAATCATCGCAGTAGCAGGTAATGGTGAACATCAAA
TTTTCTTTCTTGATTTAGAAATTAAAGGTGAAGAGCAGCAAGGGATTGATGTTGCTAAAGCTATTCGTGAAAAAAATAGC
ACAGCTATTATTGTTTTTGTGACGACACATTCTGAATTCATGCTCTTAACCTATCAATCTTTAGTAGGTGCTATTGACTT
TATTGACAAAGGATTAAACGAAGAAGCGTTTAATGAACGCTTATTCGTTTGTCTTAAAGAAGCTGTCAAACGCCAAGAGG
GAAACTTTGGTGAACATTCCTACTTGTTTCATACCCCACAAGCCAAAGTGCGGGTAGCTTATGATGATATTTTATTTTTT
GAAACGTCACCAGCACCTCATCGTATTATTTTGCACACTAAGAACGAACGTACAGAATTTTATGCGACCATAGCAGAAGT
GGCAAAATCAGATGAACGTCTTTTTAGATGTCATCGTTCTTTTGTGGTTAACGTGGATAATATCGCTAGATTTGATATGA
GGTATAAGCTCATTTATTTTGAGATGGGAGAAACCTGTCCTGTAGCTAGGGCTAAGGTGAAATTATTACAGGAGAAAATT
GAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-120)

• LytTr DNA-binding domain (LytTR) (150-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	65.823	98.34	0.647
comE/blpR	Streptococcus mutans UA159	46.281	100	0.465
comE/comE2	Streptococcus equinus JB1	44.398	100	0.444
comE/comE2	Streptococcus gordonii strain NCTC7865	35.06	100	0.365
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	35.06	100	0.365
agrA	Staphylococcus aureus N315	35.656	100	0.361