Detailed information NTG0510705

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STCNRZ302_RS01510
• Genome accession: NZ_CP065489
• Coordinates: 272071..272970 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain CNRZ302
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 267071..277970

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ302_RS01490 (STCNRZ302_01470)	trkA	268207..269556 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
STCNRZ302_RS01495 (STCNRZ302_01475)	-	269845..270354 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
STCNRZ302_RS01500 (STCNRZ302_01480)	-	270666..271223 (+)	558	WP_002949523.1	ECF transporter S component	-
STCNRZ302_RS01505 (STCNRZ302_01485)	-	271226..271876 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
STCNRZ302_RS01510 (STCNRZ302_01490)	comR	272071..272970 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
STCNRZ302_RS01515 (STCNRZ302_01495)	-	273145..275240 (+)	2096	Protein_245	peptide cleavage/export ABC transporter	-
STCNRZ302_RS01520 (STCNRZ302_01500)	-	275348..275665 (+)	318	WP_179970762.1	DUF805 domain-containing protein	-
STCNRZ302_RS01525	-	275881..276228 (-)	348	WP_232085744.1	DUF4153 domain-containing protein	-
STCNRZ302_RS01530	-	276153..276953 (-)	801	WP_232086444.1	urease cluster protein	-
STCNRZ302_RS01535 (STCNRZ302_01510)	-	277454..277969 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=510705 STCNRZ302_RS01510 WP_014607953.1 272071..272970(+) (comR) [Streptococcus thermophilus strain CNRZ302]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=510705 STCNRZ302_RS01510 WP_014607953.1 272071..272970(+) (comR) [Streptococcus thermophilus strain CNRZ302]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418