Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   STAVA1121_RS04405 Genome accession   NZ_CP065488
Coordinates   821762..822601 (+) Length   279 a.a.
NCBI ID   WP_011225887.1    Uniprot ID   Q5M4N4
Organism   Streptococcus thermophilus strain AVA1121     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 816762..827601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS04375 (STAVA1121_04305) - 817204..817704 (+) 501 WP_347131521.1 ECF transporter S component -
  STAVA1121_RS04380 (STAVA1121_04310) - 817728..818243 (+) 516 WP_180473519.1 transcription repressor NadR -
  STAVA1121_RS04385 (STAVA1121_04315) - 818338..819027 (+) 690 WP_011225885.1 helix-turn-helix transcriptional regulator -
  STAVA1121_RS04390 (STAVA1121_04320) ylqF 819155..820009 (+) 855 WP_022096554.1 ribosome biogenesis GTPase YlqF -
  STAVA1121_RS04395 (STAVA1121_04325) - 819996..820763 (+) 768 WP_347131523.1 ribonuclease HII -
  STAVA1121_RS04400 (STAVA1121_04330) - 820774..821694 (+) 921 WP_173940329.1 ROK family protein -
  STAVA1121_RS04405 (STAVA1121_04335) dprA 821762..822601 (+) 840 WP_011225887.1 DNA-processing protein DprA Machinery gene
  STAVA1121_RS04410 (STAVA1121_04340) topA 822769..824913 (+) 2145 WP_232979795.1 type I DNA topoisomerase -
  STAVA1121_RS04415 (STAVA1121_04345) - 825031..825855 (+) 825 WP_347131525.1 TraX family protein -
  STAVA1121_RS04420 (STAVA1121_04350) - 825891..826550 (+) 660 WP_011227158.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 31247.18 Da        Isoelectric Point: 8.6571

>NTDB_id=510662 STAVA1121_RS04405 WP_011225887.1 821762..822601(+) (dprA) [Streptococcus thermophilus strain AVA1121]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAVLFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVHELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHYPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDIISEFS

Nucleotide


Download         Length: 840 bp        

>NTDB_id=510662 STAVA1121_RS04405 WP_011225887.1 821762..822601(+) (dprA) [Streptococcus thermophilus strain AVA1121]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTGACGAATTTAAACATCCTTAACATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCCGTTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTTCAACGTTTTCCGACCTTATCAATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTCCTCCTCTTTTATCAAGGGAATATTGATTTGCTAAGTAAACCCAAGTT
AGCAGTAGTTGGTGCCAGAAAGTGTTCTGAAACAGGAAAACAGTCTGTTCGAAAAATTGTTCATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGCTTGGCGCGTGGAATTGATACTTGTGCTCATATGGAGGCCTTAAAAAATAAAGGTAACACCATT
GCAGTTATCGGGACTGGGCTAGACGTATATTATCCTAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTACAGAATACGGACCGGGTGAACAGCCACTTAAATACCATTATCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGGGTTATGGTGGTTGAAGCCAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGAAGA
GATGTTTTCGCCATACCAGGAAATATTTTAGATGGAAAATCGGATGGATGCCATCACCTCATTCAAGAGGGCGCAAAGTG
CATTACTACAGGATTTGACATCATTTCAGAATTTTCATAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M4N4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

72.043

100

0.72
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.309

99.642

0.631
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus mitis SK321

62.95

99.642

0.627
  dprA Lactococcus lactis subsp. cremoris KW2

60.432

99.642

0.602
  dprA Latilactobacillus sakei subsp. sakei 23K

39.768

92.832

0.369
  dprA Bacillus subtilis subsp. subtilis str. 168

48.095

75.269

0.362