Detailed information NTG0510421

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: STMM1_RS04115
• Genome accession: NZ_CP065484
• Coordinates: 773084..773791 (+)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM1
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 768084..778791

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM1_RS04085 (STMM1_04045)	-	768365..768553 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STMM1_RS04090 (STMM1_04050)	endA	768615..769496 (+)	882	WP_071417356.1	DNA/RNA non-specific endonuclease	Machinery gene
STMM1_RS04095 (STMM1_04055)	-	769567..770217 (-)	651	WP_014608375.1	amino acid ABC transporter permease	-
STMM1_RS04100 (STMM1_04060)	-	770229..770927 (-)	699	WP_014608374.1	amino acid ABC transporter permease	-
STMM1_RS04105 (STMM1_04065)	-	770945..771778 (-)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
STMM1_RS04110 (STMM1_04070)	-	771790..772557 (-)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
STMM1_RS04115 (STMM1_04075)	vicR	773084..773791 (+)	708	WP_011681206.1	response regulator YycF	Regulator
STMM1_RS04120 (STMM1_04080)	vicK	773784..775124 (+)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
STMM1_RS04125 (STMM1_04085)	vicX	775130..775942 (+)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
STMM1_RS04130 (STMM1_04090)	-	776002..776363 (+)	362	Protein_754	YbaN family protein	-
STMM1_RS04135 (STMM1_04095)	-	776415..777629 (-)	1215	WP_002953123.1	aminoacyltransferase	-
STMM1_RS04140 (STMM1_04100)	yidA	777631..778440 (-)	810	WP_071417357.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=510421 STMM1_RS04115 WP_011681206.1 773084..773791(+) (vicR) [Streptococcus thermophilus strain MM1]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=510421 STMM1_RS04115 WP_011681206.1 773084..773791(+) (vicR) [Streptococcus thermophilus strain MM1]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387