Detailed information NTG0510323

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: STCNRZ760_RS07510
• Genome accession: NZ_CP065482
• Coordinates: 1443386..1444081 (-)
• Length: 231 a.a.
• NCBI ID: WP_082309090.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ760
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1438386..1449081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ760_RS07495 (STCNRZ760_07435)	-	1439197..1439742 (-)	546	WP_022096992.1	GNAT family N-acetyltransferase	-
STCNRZ760_RS07500 (STCNRZ760_07440)	-	1439808..1441070 (-)	1263	WP_022096991.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ760_RS07505 (STCNRZ760_07445)	-	1441156..1443396 (-)	2241	WP_180481070.1	DNA internalization-related competence protein ComEC/Rec2	-
STCNRZ760_RS07510 (STCNRZ760_07450)	comEA	1443386..1444081 (-)	696	WP_082309090.1	helix-hairpin-helix domain-containing protein	Machinery gene
STCNRZ760_RS07515 (STCNRZ760_07455)	-	1444189..1444944 (-)	756	WP_002948862.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
STCNRZ760_RS07520	-	1445435..1445673 (+)	239	Protein_1428	polysaccharide deacetylase family protein	-
STCNRZ760_RS07525	-	1445722..1446000 (+)	279	WP_002948857.1	hypothetical protein	-
STCNRZ760_RS07530 (STCNRZ760_07465)	-	1446016..1447272 (-)	1257	Protein_1430	ISL3-like element ISSth1 family transposase	-
STCNRZ760_RS07535 (STCNRZ760_07470)	-	1447483..1448235 (+)	753	WP_002948852.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
STCNRZ760_RS07540 (STCNRZ760_07475)	-	1448252..1448521 (+)	270	WP_002948849.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 24514.46 Da
• Isoelectric Point: 4.6300

>NTDB_id=510323 STCNRZ760_RS07510 WP_082309090.1 1443386..1444081(-) (comEA) [Streptococcus thermophilus strain CNRZ760]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide

• Length: 696 bp

>NTDB_id=510323 STCNRZ760_RS07510 WP_082309090.1 1443386..1444081(-) (comEA) [Streptococcus thermophilus strain CNRZ760]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (85-138)

• Helix-hairpin-helix motif (HHH_3) (167-228)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	99.134	100	0.991
comEA/celA/cilE	Streptococcus mitis SK321	40.611	99.134	0.403
comEA/celA/cilE	Streptococcus pneumoniae D39	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus pneumoniae R6	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus pneumoniae Rx1	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus mitis NCTC 12261	37.719	98.701	0.372