Detailed information NTG0510216

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ST90729_RS08845
• Genome accession: NZ_CP065480
• Coordinates: 1710992..1712092 (-)
• Length: 366 a.a.
• NCBI ID: WP_271307389.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 90729
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1705992..1717092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST90729_RS08805 (ST90729_08770)	-	1706604..1706801 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
ST90729_RS08810 (ST90729_08775)	-	1707050..1708243 (-)	1194	WP_014608740.1	acetate kinase	-
ST90729_RS08815 (ST90729_08780)	comYH	1708299..1709255 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST90729_RS08820 (ST90729_08785)	comGG	1709300..1709617 (-)	318	WP_141326604.1	competence type IV pilus minor pilin ComGG	-
ST90729_RS08825 (ST90729_08790)	comYF	1709595..1710032 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST90729_RS08830 (ST90729_08795)	comGE	1710016..1710309 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST90729_RS08835 (ST90729_08800)	comYD	1710281..1710709 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST90729_RS08840 (ST90729_08805)	comYC	1710669..1710995 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST90729_RS08845 (ST90729_08810)	comYB	1710992..1712092 (-)	1101	WP_271307389.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST90729_RS08850 (ST90729_08815)	comGA/cglA/cilD	1711974..1712915 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
ST90729_RS08855 (ST90729_08820)	-	1712996..1713358 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41806.92 Da
• Isoelectric Point: 10.1084

>NTDB_id=510216 ST90729_RS08845 WP_271307389.1 1710992..1712092(-) (comYB) [Streptococcus thermophilus strain 90729]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRHSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=510216 ST90729_RS08845 WP_271307389.1 1710992..1712092(-) (comYB) [Streptococcus thermophilus strain 90729]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACATTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	50.877	93.443	0.475
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413