Detailed information NTG0509974

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ST4052_RS08495
• Genome accession: NZ_CP065476
• Coordinates: 1633232..1634332 (-)
• Length: 366 a.a.
• NCBI ID: WP_148148900.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4052
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1628232..1639332

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4052_RS08455 (ST4052_08520)	-	1628844..1629041 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
ST4052_RS08460 (ST4052_08525)	-	1629290..1630483 (-)	1194	WP_022096898.1	acetate kinase	-
ST4052_RS08465 (ST4052_08530)	comYH	1630539..1631495 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST4052_RS08470 (ST4052_08535)	comGG	1631540..1631857 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
ST4052_RS08475 (ST4052_08540)	comYF	1631835..1632272 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST4052_RS08480 (ST4052_08545)	comGE	1632256..1632549 (-)	294	WP_347100874.1	competence type IV pilus minor pilin ComGE	-
ST4052_RS08485 (ST4052_08550)	comYD	1632521..1632949 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST4052_RS08490 (ST4052_08555)	comYC	1632909..1633235 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST4052_RS08495 (ST4052_08560)	comYB	1633232..1634332 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST4052_RS08500 (ST4052_08565)	comGA/cglA/cilD	1634214..1635155 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
ST4052_RS08505 (ST4052_08570)	-	1635236..1635598 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41754.88 Da
• Isoelectric Point: 10.0449

>NTDB_id=509974 ST4052_RS08495 WP_148148900.1 1633232..1634332(-) (comYB) [Streptococcus thermophilus strain 4052]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=509974 ST4052_RS08495 WP_148148900.1 1633232..1634332(-) (comYB) [Streptococcus thermophilus strain 4052]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.394	90.164	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413