Detailed information NTG0509538

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: I5V48_RS11935
• Genome accession: NZ_CP065430
• Coordinates: 2493724..2494920 (+)
• Length: 398 a.a.
• NCBI ID: WP_043024644.1
• Uniprot ID: -
• Organism: Streptococcus suis strain YZDH1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2488724..2499920

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I5V48_RS11900 (I5V48_11900)	-	2490347..2490682 (+)	336	WP_306172866.1	helix-turn-helix domain-containing protein	-
I5V48_RS11905 (I5V48_11905)	-	2490785..2491858 (+)	1074	WP_043025828.1	site-specific integrase	-
I5V48_RS11925 (I5V48_11925)	-	2492363..2493046 (-)	684	WP_043024643.1	YoaK family protein	-
I5V48_RS11930 (I5V48_11930)	rlmH	2493071..2493550 (-)	480	WP_002941741.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
I5V48_RS11935 (I5V48_11935)	htrA	2493724..2494920 (+)	1197	WP_043024644.1	S1C family serine protease	Regulator
I5V48_RS11940 (I5V48_11940)	spo0J	2494981..2495745 (+)	765	WP_004195351.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41850.93 Da
• Isoelectric Point: 4.5454

>NTDB_id=509538 I5V48_RS11935 WP_043024644.1 2493724..2494920(+) (htrA) [Streptococcus suis strain YZDH1]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKAGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGETIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=509538 I5V48_RS11935 WP_043024644.1 2493724..2494920(+) (htrA) [Streptococcus suis strain YZDH1]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
AGCCTTATCAGCCTCTTTCTTCCAACCACAGGTGCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTCATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCTAATACAGTTACTCAAGGTATTATTTCTAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ATGGTCAAACAATCTCAACCAACGCTATTCAAACCGATACAGCTATCAACCCTGGAAACTCTGGAGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCAGGGGTGGCTGTGGAAGG
GATGGGATTCGCTATTCCTGCAAATGATGCCGTAGCCATTATCAATCAACTTGAGAAAGCTGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAACTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.453	99.749	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	60.253	99.246	0.598
htrA	Streptococcus pneumoniae D39	57.506	98.744	0.568
htrA	Streptococcus pneumoniae TIGR4	57.506	98.744	0.568
htrA	Streptococcus mitis NCTC 12261	57.506	98.744	0.568
htrA	Streptococcus pneumoniae R6	57.506	98.744	0.568
htrA	Streptococcus pneumoniae Rx1	57.506	98.744	0.568