Detailed information
Bioinformatically predicted
Overview
| Name | comB | Type | Regulator |
| Locus tag | MYY_RS00625 | Genome accession | NC_017769 |
| Coordinates | 100874..102223 (+) | Length | 449 a.a. |
| NCBI ID | WP_000801629.1 | Uniprot ID | A0A0T8X0V4 |
| Organism | Streptococcus pneumoniae ST556 | ||
| Function | transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 30942..112328 | 100874..102223 | within | 0 |
Gene organization within MGE regions
Location: 30942..112328
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MYY_RS00210 (MYY_0042) | ftsH | 30942..32900 (+) | 1959 | WP_000744557.1 | ATP-dependent zinc metalloprotease FtsH | - |
| MYY_RS00215 (MYY_0043) | comX/comX2 | 33022..33501 (+) | 480 | WP_000588897.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| MYY_RS11410 | - | 39050..39259 (+) | 210 | Protein_45 | transposase | - |
| MYY_RS11415 | - | 39294..40091 (-) | 798 | Protein_46 | transposase | - |
| MYY_RS00260 (MYY_0046) | comW | 40357..40593 (+) | 237 | WP_000939544.1 | sigma(X)-activator ComW | Regulator |
| MYY_RS00265 (MYY_0047) | - | 40824..42110 (+) | 1287 | WP_000205044.1 | adenylosuccinate synthase | - |
| MYY_RS00270 (MYY_0048) | tadA | 42311..42778 (+) | 468 | WP_000291879.1 | tRNA adenosine(34) deaminase TadA | - |
| MYY_RS00275 (MYY_0049) | - | 42987..44129 (-) | 1143 | WP_000266852.1 | tyrosine-type recombinase/integrase | - |
| MYY_RS00280 (MYY_0050) | - | 44248..44598 (-) | 351 | WP_001020945.1 | hypothetical protein | - |
| MYY_RS00285 (MYY_0051) | - | 44652..44864 (-) | 213 | WP_014678321.1 | hypothetical protein | - |
| MYY_RS00290 (MYY_0052) | - | 44886..45242 (-) | 357 | WP_000153672.1 | helix-turn-helix domain-containing protein | - |
| MYY_RS00295 (MYY_0053) | - | 45518..45703 (+) | 186 | WP_000638668.1 | helix-turn-helix domain-containing protein | - |
| MYY_RS00300 (MYY_0054) | - | 45705..46403 (+) | 699 | WP_001004041.1 | phage antirepressor KilAC domain-containing protein | - |
| MYY_RS11425 | - | 46663..46899 (-) | 237 | WP_001811944.1 | hypothetical protein | - |
| MYY_RS00315 (MYY_0057) | - | 47577..47843 (+) | 267 | WP_000450962.1 | hypothetical protein | - |
| MYY_RS00320 (MYY_0058) | - | 47927..48379 (+) | 453 | WP_001134283.1 | hypothetical protein | - |
| MYY_RS00325 (MYY_0059) | - | 48385..49086 (+) | 702 | WP_000774580.1 | ERF family protein | - |
| MYY_RS00330 (MYY_0060) | - | 49089..50081 (+) | 993 | WP_000237815.1 | DUF1351 domain-containing protein | - |
| MYY_RS12905 | - | 50103..50279 (+) | 177 | WP_001203349.1 | hypothetical protein | - |
| MYY_RS00335 (MYY_0062) | ssb | 50269..50844 (+) | 576 | WP_000609578.1 | single-stranded DNA-binding protein | Machinery gene |
| MYY_RS00340 (MYY_0063) | - | 50870..52108 (+) | 1239 | WP_000670027.1 | DNA cytosine methyltransferase | - |
| MYY_RS00345 (MYY_02235) | - | 52143..52346 (+) | 204 | WP_000161129.1 | hypothetical protein | - |
| MYY_RS00350 (MYY_0064) | - | 52374..52553 (+) | 180 | Protein_65 | hypothetical protein | - |
| MYY_RS00355 (MYY_0065) | - | 52570..52782 (+) | 213 | WP_001286809.1 | crAss001_48 related protein | - |
| MYY_RS00360 (MYY_0066) | - | 52793..53194 (+) | 402 | WP_000667209.1 | hypothetical protein | - |
| MYY_RS00365 (MYY_0067) | - | 53196..53402 (+) | 207 | WP_000573750.1 | hypothetical protein | - |
| MYY_RS00370 (MYY_0068) | - | 53451..53768 (+) | 318 | WP_000969685.1 | hypothetical protein | - |
| MYY_RS00375 (MYY_0069) | - | 53770..54285 (+) | 516 | WP_001021768.1 | DUF1642 domain-containing protein | - |
| MYY_RS00380 (MYY_0070) | - | 54286..54498 (+) | 213 | WP_000160161.1 | hypothetical protein | - |
| MYY_RS00385 (MYY_02240) | - | 54495..54866 (+) | 372 | WP_001247149.1 | hypothetical protein | - |
| MYY_RS00390 (MYY_02245) | - | 54887..55180 (+) | 294 | WP_000194856.1 | hypothetical protein | - |
| MYY_RS00395 (MYY_0072) | - | 55180..55572 (+) | 393 | WP_000162611.1 | hypothetical protein | - |
| MYY_RS00400 (MYY_0073) | - | 55638..56732 (+) | 1095 | WP_000425574.1 | DUF4417 domain-containing protein | - |
| MYY_RS00405 (MYY_0074) | - | 56713..57459 (+) | 747 | WP_000057535.1 | hypothetical protein | - |
| MYY_RS00410 (MYY_0075) | - | 57663..58118 (+) | 456 | WP_001136855.1 | KGG domain-containing protein | - |
| MYY_RS00415 (MYY_0076) | - | 58108..59418 (+) | 1311 | WP_000143806.1 | PBSX family phage terminase large subunit | - |
| MYY_RS00420 (MYY_0077) | - | 59431..60999 (+) | 1569 | WP_000051858.1 | phage portal protein | - |
| MYY_RS12910 | - | 60986..61159 (+) | 174 | WP_000169861.1 | hypothetical protein | - |
| MYY_RS00425 (MYY_0078) | - | 61202..62353 (+) | 1152 | WP_000730217.1 | phage minor capsid protein | - |
| MYY_RS00430 (MYY_0079) | - | 62492..63055 (+) | 564 | WP_000896122.1 | phage scaffolding protein | - |
| MYY_RS00435 (MYY_0080) | - | 63073..63954 (+) | 882 | WP_001139823.1 | hypothetical protein | - |
| MYY_RS00440 (MYY_0081) | - | 63965..64198 (+) | 234 | WP_001240344.1 | hypothetical protein | - |
| MYY_RS00445 (MYY_0082) | - | 64241..64633 (+) | 393 | WP_000221836.1 | hypothetical protein | - |
| MYY_RS00450 (MYY_02250) | - | 64623..64994 (+) | 372 | WP_000565934.1 | putative minor capsid protein | - |
| MYY_RS00455 (MYY_0084) | - | 64994..65338 (+) | 345 | WP_000020371.1 | minor capsid protein | - |
| MYY_RS00460 (MYY_0085) | - | 65338..65745 (+) | 408 | WP_001208881.1 | minor capsid protein | - |
| MYY_RS00465 (MYY_0086) | - | 65742..66191 (+) | 450 | WP_000198229.1 | phage tail tube protein | - |
| MYY_RS00470 (MYY_0087) | - | 66256..66744 (+) | 489 | WP_000129839.1 | hypothetical protein | - |
| MYY_RS00475 (MYY_0088) | - | 66757..67326 (+) | 570 | WP_000062053.1 | Gp15 family bacteriophage protein | - |
| MYY_RS00480 (MYY_0089) | - | 67319..70600 (+) | 3282 | WP_001279483.1 | tape measure protein | - |
| MYY_RS00485 (MYY_0090) | - | 70597..72111 (+) | 1515 | WP_000161549.1 | distal tail protein Dit | - |
| MYY_RS00490 | - | 72113..78583 (+) | 6471 | WP_053039873.1 | phage tail protein | - |
| MYY_RS00495 (MYY_0092) | - | 78595..80673 (+) | 2079 | WP_000159969.1 | DUF859 family phage minor structural protein | - |
| MYY_RS00500 (MYY_0093) | - | 80733..80996 (+) | 264 | WP_000922100.1 | hypothetical protein | - |
| MYY_RS00505 (MYY_0094) | - | 81006..81422 (+) | 417 | WP_000687457.1 | phage holin family protein | - |
| MYY_RS00510 (MYY_0095) | - | 81426..81758 (+) | 333 | WP_001186225.1 | phage holin | - |
| MYY_RS00515 (MYY_0096) | lytA | 81762..82718 (+) | 957 | WP_000350491.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| MYY_RS00520 (MYY_0097) | - | 82998..83441 (+) | 444 | WP_000701992.1 | dUTP diphosphatase | - |
| MYY_RS00525 (MYY_0098) | - | 83443..83958 (+) | 516 | WP_000691236.1 | histidine phosphatase family protein | - |
| MYY_RS00530 (MYY_0099) | radA | 83972..85333 (+) | 1362 | WP_073076903.1 | DNA repair protein RadA | Machinery gene |
| MYY_RS00535 (MYY_0100) | - | 85406..85903 (+) | 498 | WP_001809263.1 | beta-class carbonic anhydrase | - |
| MYY_RS00540 (MYY_0101) | - | 85928..86743 (+) | 816 | WP_000749768.1 | PrsW family intramembrane metalloprotease | - |
| MYY_RS00545 (MYY_0102) | - | 86888..87856 (+) | 969 | WP_000010163.1 | ribose-phosphate diphosphokinase | - |
| MYY_RS11430 | - | 87990..88271 (-) | 282 | Protein_106 | ISL3 family transposase | - |
| MYY_RS13160 | - | 88400..89307 (-) | 908 | Protein_107 | Rpn family recombination-promoting nuclease/putative transposase | - |
| MYY_RS00565 (MYY_0106) | polA | 89563..92196 (+) | 2634 | WP_000358436.1 | DNA polymerase I | - |
| MYY_RS00570 (MYY_0107) | - | 92281..92718 (+) | 438 | WP_000076479.1 | CoA-binding protein | - |
| MYY_RS00575 (MYY_0108) | - | 92901..93911 (-) | 1011 | WP_000009178.1 | YeiH family protein | - |
| MYY_RS00580 (MYY_0109) | - | 94060..95229 (+) | 1170 | WP_000366375.1 | pyridoxal phosphate-dependent aminotransferase | - |
| MYY_RS00585 (MYY_0110) | recO | 95226..95996 (+) | 771 | WP_000616166.1 | DNA repair protein RecO | - |
| MYY_RS00590 (MYY_0111) | plsX | 95993..96985 (+) | 993 | WP_000717456.1 | phosphate acyltransferase PlsX | - |
| MYY_RS00595 (MYY_0112) | - | 96991..97224 (+) | 234 | WP_000136447.1 | acyl carrier protein | - |
| MYY_RS00600 (MYY_0113) | - | 97261..97560 (+) | 300 | Protein_115 | transposase family protein | - |
| MYY_RS00605 (MYY_0114) | blpU | 97763..97993 (+) | 231 | WP_001093071.1 | bacteriocin-like peptide BlpU | - |
| MYY_RS13500 (MYY_0115) | - | 97996..98121 (+) | 126 | WP_000346297.1 | PncF family bacteriocin immunity protein | - |
| MYY_RS00620 (MYY_0116) | comA | 98708..100861 (+) | 2154 | WP_000668293.1 | peptide cleavage/export ABC transporter ComA | Regulator |
| MYY_RS00625 (MYY_0117) | comB | 100874..102223 (+) | 1350 | WP_000801629.1 | competence pheromone export protein ComB | Regulator |
| MYY_RS00630 (MYY_0118) | purC | 102393..103100 (+) | 708 | WP_000043313.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| MYY_RS13610 (MYY_0119) | - | 103111..103245 (+) | 135 | WP_000429436.1 | hypothetical protein | - |
| MYY_RS00640 (MYY_0120) | - | 103302..107027 (+) | 3726 | WP_000361166.1 | phosphoribosylformylglycinamidine synthase | - |
| MYY_RS00645 (MYY_0121) | purF | 107120..108562 (+) | 1443 | WP_000220633.1 | amidophosphoribosyltransferase | - |
| MYY_RS00650 (MYY_0122) | purM | 108599..109621 (+) | 1023 | WP_000182580.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| MYY_RS00655 (MYY_0123) | purN | 109618..110163 (+) | 546 | WP_000717501.1 | phosphoribosylglycinamide formyltransferase | - |
| MYY_RS00660 (MYY_0124) | - | 110247..110756 (+) | 510 | WP_000894002.1 | VanZ family protein | - |
| MYY_RS00665 (MYY_0125) | purH | 110781..112328 (+) | 1548 | WP_000167081.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 49525.39 Da Isoelectric Point: 5.5618
>NTDB_id=50799 MYY_RS00625 WP_000801629.1 100874..102223(+) (comB) [Streptococcus pneumoniae ST556]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQGGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGTLLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQGGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGTLLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE
Nucleotide
Download Length: 1350 bp
>NTDB_id=50799 MYY_RS00625 WP_000801629.1 100874..102223(+) (comB) [Streptococcus pneumoniae ST556]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGGAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGTGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTACCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTAGATCAATTTTTGAACAAAGAGTAA
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGGAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGTGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTACCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTAGATCAATTTTTGAACAAAGAGTAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB | Streptococcus pneumoniae Rx1 |
99.332 |
100 |
0.993 |
| comB | Streptococcus pneumoniae D39 |
99.332 |
100 |
0.993 |
| comB | Streptococcus pneumoniae R6 |
99.332 |
100 |
0.993 |
| comB | Streptococcus pneumoniae TIGR4 |
99.109 |
100 |
0.991 |
| comB | Streptococcus mitis SK321 |
95.1 |
100 |
0.951 |
| comB | Streptococcus mitis NCTC 12261 |
94.209 |
100 |
0.942 |
| comB | Streptococcus gordonii str. Challis substr. CH1 |
55.778 |
100 |
0.559 |