Detailed information NTG0050781

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SMULJ23_RS08590
• Genome accession: NC_017768
• Coordinates: 1772904..1775186 (-)
• Length: 760 a.a.
• NCBI ID: WP_002263523.1
• Uniprot ID: Q8DW05
• Organism: Streptococcus mutans LJ23
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1767904..1780186

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMULJ23_RS08575 (SMULJ23_1680)	ulaG	1768295..1769386 (-)	1092	WP_002263526.1	L-ascorbate 6-phosphate lactonase	-
SMULJ23_RS08580 (SMULJ23_1681)	-	1769965..1771629 (-)	1665	WP_014678235.1	transcription antiterminator	-
SMULJ23_RS08585 (SMULJ23_1682)	comB/nlmE	1771979..1772890 (-)	912	WP_014678236.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
SMULJ23_RS08590 (SMULJ23_1683)	comA/nlmT	1772904..1775186 (-)	2283	WP_002263523.1	peptide cleavage/export ABC transporter	Regulator
SMULJ23_RS08595 (SMULJ23_1686)	-	1776443..1776721 (-)	279	WP_014678238.1	hypothetical protein	-
SMULJ23_RS08600 (SMULJ23_1687)	-	1776959..1777168 (-)	210	WP_002292070.1	hypothetical protein	-
SMULJ23_RS10260 (SMULJ23_1688)	-	1777642..1777803 (-)	162	WP_162470319.1	hypothetical protein	-
SMULJ23_RS08605	-	1778070..1778477 (-)	408	WP_044560724.1	hypothetical protein	-
SMULJ23_RS08610 (SMULJ23_1691)	-	1778496..1778714 (-)	219	WP_014678241.1	Blp family class II bacteriocin	-
SMULJ23_RS10520 (SMULJ23_1692)	-	1778995..1779177 (-)	183	WP_014678242.1	hypothetical protein	-
SMULJ23_RS08615 (SMULJ23_1694)	-	1779391..1779666 (-)	276	WP_014678243.1	hypothetical protein	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85096.79 Da
• Isoelectric Point: 8.9095

>NTDB_id=50781 SMULJ23_RS08590 WP_002263523.1 1772904..1775186(-) (comA/nlmT) [Streptococcus mutans LJ23]
MKQVIYVVLIVIAVNILLEIIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRHISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=50781 SMULJ23_RS08590 WP_002263523.1 1772904..1775186(-) (comA/nlmT) [Streptococcus mutans LJ23]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGATTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGATCTAATTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCATCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTAATTCTGGTTGGCGGAGTTTTATTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCTATTCCGATTTATGCCATCATTATTTTTGCTTTCTTAAAGCCTTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTCTGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAGGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGCGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAGACAACTTTGGCTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGCATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAGGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACACAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAAGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (50-186)

• ABC transporter (ABC_tran) (544-693)

• ABC transporter transmembrane region (ABC_membrane) (212-481)

3D structure

• PDB: 3K8U
• PDB: 3VX4
• PDB: 5XE8
• PDB: 5XE9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	100	100	1
comA	Streptococcus mitis NCTC 12261	65.411	94.342	0.617
comA	Streptococcus pneumoniae Rx1	64.854	94.342	0.612
comA	Streptococcus pneumoniae D39	64.854	94.342	0.612
comA	Streptococcus pneumoniae R6	64.854	94.342	0.612
comA	Streptococcus mitis SK321	64.714	94.342	0.611
comA	Streptococcus pneumoniae TIGR4	64.575	94.342	0.609
comA	Streptococcus gordonii str. Challis substr. CH1	64.435	94.342	0.608