Detailed information NTG0506577

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: I2437_RS00280
• Genome accession: NZ_CP065061
• Coordinates: 48041..48955 (+)
• Length: 304 a.a.
• NCBI ID: WP_206157860.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ33
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 43041..53955

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2437_RS00260 (IEMOCGPF_00052)	purE	44204..44692 (+)	489	WP_206157859.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
I2437_RS00265 (IEMOCGPF_00053)	purK	44679..45770 (+)	1092	WP_165627994.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
I2437_RS00270 (IEMOCGPF_00054)	-	45780..46004 (+)	225	WP_037582407.1	hypothetical protein	-
I2437_RS09735	-	46029..46100 (+)	72	Protein_34	hypothetical protein	-
I2437_RS00275 (IEMOCGPF_00055)	purB	46450..47742 (+)	1293	WP_038674659.1	adenylosuccinate lyase	-
I2437_RS00280 (IEMOCGPF_00056)	comR	48041..48955 (+)	915	WP_206157860.1	XRE family transcriptional regulator	Regulator
I2437_RS00290 (IEMOCGPF_00058)	ruvB	49170..50177 (+)	1008	WP_043039894.1	Holliday junction branch migration DNA helicase RuvB	-
I2437_RS00295 (IEMOCGPF_00059)	-	50418..50876 (+)	459	WP_012677206.1	low molecular weight protein-tyrosine-phosphatase	-
I2437_RS00300 (IEMOCGPF_00060)	-	50882..51283 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
I2437_RS00305 (IEMOCGPF_00061)	-	51280..53061 (+)	1782	WP_206157861.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35852.33 Da
• Isoelectric Point: 4.5175

>NTDB_id=506577 I2437_RS00280 WP_206157860.1 48041..48955(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSTKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWDKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=506577 I2437_RS00280 WP_206157860.1 48041..48955(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGATATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCACCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCGTGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTAAGAG
AAGAGTGGGATAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.153	99.013	0.536
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.498	98.355	0.487
comR	Streptococcus suis D9	37.874	99.013	0.375
comR	Streptococcus suis P1/7	38.644	97.039	0.375
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375