Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   I2436_RS07475 Genome accession   NZ_CP065060
Coordinates   1600918..1603080 (+) Length   720 a.a.
NCBI ID   WP_206152751.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1595918..1608080
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS07430 - 1595980..1596219 (+) 240 WP_043984241.1 helix-turn-helix transcriptional regulator -
  I2436_RS07435 (GDAKBCAL_01493) - 1596321..1596902 (-) 582 WP_165627810.1 GNAT family N-acetyltransferase -
  I2436_RS07440 (GDAKBCAL_01494) - 1597153..1597554 (-) 402 WP_230923698.1 bacteriocin immunity protein -
  I2436_RS07445 (GDAKBCAL_01495) - 1598227..1598430 (-) 204 WP_012516109.1 Blp family class II bacteriocin -
  I2436_RS07450 (GDAKBCAL_01496) - 1598447..1598701 (-) 255 WP_111692691.1 Blp family class II bacteriocin -
  I2436_RS07455 (GDAKBCAL_01497) - 1598854..1599150 (-) 297 WP_012516111.1 bacteriocin immunity protein -
  I2436_RS07460 (GDAKBCAL_01498) - 1599150..1599368 (-) 219 WP_021321057.1 leucocin A/sakacin P family class II bacteriocin -
  I2436_RS07465 (GDAKBCAL_01499) - 1600106..1600405 (-) 300 WP_041790663.1 bacteriocin immunity protein -
  I2436_RS07470 (GDAKBCAL_01500) - 1600412..1600660 (-) 249 WP_012677516.1 garvicin Q family class II bacteriocin -
  I2436_RS07475 (GDAKBCAL_01501) comA/nlmT 1600918..1603080 (+) 2163 WP_206152751.1 peptide cleavage/export ABC transporter Regulator
  I2436_RS07480 (GDAKBCAL_01502) - 1603091..1604449 (+) 1359 WP_206152752.1 bacteriocin secretion accessory protein -
  I2436_RS07485 (GDAKBCAL_01503) - 1604549..1604683 (+) 135 WP_126436990.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I2436_RS07490 (GDAKBCAL_01504) - 1604802..1606136 (-) 1335 WP_165623392.1 GHKL domain-containing protein -
  I2436_RS07495 (GDAKBCAL_01505) comE/blpR 1606136..1606885 (-) 750 WP_042671079.1 response regulator transcription factor Regulator
  I2436_RS07500 (GDAKBCAL_01506) - 1607512..1607706 (-) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I2436_RS07505 (GDAKBCAL_01507) - 1607723..1607980 (-) 258 WP_043030068.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 720 a.a.        Molecular weight: 80877.07 Da        Isoelectric Point: 7.7847

>NTDB_id=506555 I2436_RS07475 WP_206152751.1 1600918..1603080(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPQPHKDQKNGLLGF
FPLIFKQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRL
TIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPV
YTLIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQG
AQLILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDL
SLLQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLR
QYINYLPQQAYIFNGSILENLTLGAKQGISQEDIFKACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLT
QAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2163 bp        

>NTDB_id=506555 I2436_RS07475 WP_206152751.1 1600918..1603080(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCCTCAATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATGGGATTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCAGAATGGACAG
GTGTCACCATATGTCTTGCTCCTAAGCCAAATTATAAACCACAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTC
TTTCCGCTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTGC
TGGTTCATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTG
GTCTCATCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTT
ACGATTGATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGA
GGTAACCTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCT
CTATATTAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATCCCAGTA
TATACCCTTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAG
CTCTGCTATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTG
ACAGCGACTTTGTGGATTACCTCGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGA
GCGCAGCTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATCGGGCAGTT
AATTACCTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAG
CTAAGGTTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTA
TCGCTCTTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTATAGGTATGGCTTTGGCAAGGATACATTATCAGATATTAC
ATTAACCATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCG
TCAATTTCTTTGAGCCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGA
CAATACATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCA
GGGCATCAGCCAGGAAGACATTTTTAAAGCCTGTGAGATTGCTGATATTCGTCACGACATCGAGCAAATGCCAATGGGAT
ACCAAACCGAACTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACC
CAAGCTCCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCAT
GAACATGACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTTGTTCTTA
ATCAAGGGCAAATCATTGAGACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAA
TAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter (ABC_tran)

(503-652)

ABC transporter transmembrane region (ABC_membrane)

(171-441)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.515

99.861

0.704
  comA Streptococcus mitis SK321

67.273

99.306

0.668
  comA Streptococcus mitis NCTC 12261

66.993

99.306

0.665
  comA Streptococcus pneumoniae Rx1

66.573

99.306

0.661
  comA Streptococcus pneumoniae D39

66.573

99.306

0.661
  comA Streptococcus pneumoniae R6

66.573

99.306

0.661
  comA Streptococcus pneumoniae TIGR4

66.294

99.306

0.658
  comA Streptococcus gordonii str. Challis substr. CH1

65.035

99.306

0.646