Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   I2436_RS07495 Genome accession   NZ_CP065060
Coordinates   1606136..1606885 (-) Length   249 a.a.
NCBI ID   WP_042671079.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1601136..1611885
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS07480 (GDAKBCAL_01502) - 1603091..1604449 (+) 1359 WP_206152752.1 bacteriocin secretion accessory protein -
  I2436_RS07485 (GDAKBCAL_01503) - 1604549..1604683 (+) 135 WP_126436990.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I2436_RS07490 (GDAKBCAL_01504) - 1604802..1606136 (-) 1335 WP_165623392.1 GHKL domain-containing protein -
  I2436_RS07495 (GDAKBCAL_01505) comE/blpR 1606136..1606885 (-) 750 WP_042671079.1 response regulator transcription factor Regulator
  I2436_RS07500 (GDAKBCAL_01506) - 1607512..1607706 (-) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I2436_RS07505 (GDAKBCAL_01507) - 1607723..1607980 (-) 258 WP_043030068.1 Blp family class II bacteriocin -
  I2436_RS07510 (GDAKBCAL_01508) rlmD 1608301..1609668 (-) 1368 WP_206152753.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  I2436_RS07515 (GDAKBCAL_01509) - 1609665..1610633 (-) 969 WP_012516123.1 helix-hairpin-helix domain-containing protein -
  I2436_RS07520 (GDAKBCAL_01510) recX 1610697..1611473 (+) 777 WP_206152754.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29227.69 Da        Isoelectric Point: 8.4602

>NTDB_id=506556 I2436_RS07495 WP_042671079.1 1606136..1606885(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=506556 I2436_RS07495 WP_042671079.1 1606136..1606885(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGCCTCATCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

100

0.526
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386