Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   I2436_RS02530 Genome accession   NZ_CP065060
Coordinates   515525..516892 (+) Length   455 a.a.
NCBI ID   WP_206152986.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 510525..521892
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS02505 (GDAKBCAL_00499) - 511123..512016 (+) 894 WP_206152984.1 XRE family transcriptional regulator -
  I2436_RS02510 (GDAKBCAL_00501) - 512369..512509 (+) 141 WP_012515166.1 hypothetical protein -
  I2436_RS02515 (GDAKBCAL_00502) - 512622..512780 (+) 159 WP_021320463.1 hypothetical protein -
  I2436_RS02520 (GDAKBCAL_00504) - 512963..513130 (+) 168 WP_012515168.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I2436_RS02525 (GDAKBCAL_00505) comA 513357..515510 (+) 2154 WP_012515169.1 peptide cleavage/export ABC transporter ComA Regulator
  I2436_RS02530 (GDAKBCAL_00506) comB 515525..516892 (+) 1368 WP_206152986.1 bacteriocin secretion accessory protein Regulator
  I2436_RS02535 (GDAKBCAL_00507) - 517401..517637 (+) 237 WP_024273149.1 hypothetical protein -
  I2436_RS02540 (GDAKBCAL_00508) nrdF 518095..519108 (+) 1014 WP_012678369.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
  I2436_RS02545 (GDAKBCAL_00509) nrdI 519110..519520 (+) 411 WP_043052823.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  I2436_RS02550 (GDAKBCAL_00510) nrdE 519566..521740 (+) 2175 WP_111689917.1 class 1b ribonucleoside-diphosphate reductase subunit alpha -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50773.89 Da        Isoelectric Point: 5.0659

>NTDB_id=506533 I2436_RS02530 WP_206152986.1 515525..516892(+) (comB) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MNNNILESAEFYNRRYHNFSSCIILPTLLLFLFGVFFLAFAKKEISIISTATVEPNIILSNIQSTSNNTILTNNLKDNKY
VKFGDLLIKYDSRKEGIQQETYQTQLNNLQIQKEQLELLKASIEAGNSQFPEKDNYGYYQTFIDYLNQINTLSANVNQQN
ENVSSQNTAASNQQVEIENAIKGLTSQISDYQSVRSAIQNGTVVDLDNRAYSIYRSYLTQTSSLVDNTDKTAVINQFVAQ
IDSQINQLESSVAGYRIQHAGSGVQQSYSSTLESQLASLKAQSITKVEQELSALSNQITELEGTNKLQKNTSSKTSIVAN
EDGVLHLNQEFIGANIVPEGTIFAQVYPEMKKGTVVKITGYLPSTEISSISIGDTARFSTKDDNGETLDLIVKLSSIDNA
ATKTKNGNYFKVESKLQLKEKEAQLLKYGLEGKFILITGTKSYLNYYIDKFIGEK

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=506533 I2436_RS02530 WP_206152986.1 515525..516892(+) (comB) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGAATAACAATATATTAGAAAGTGCGGAATTTTATAACCGTCGTTACCACAACTTTTCTAGTTGTATCATTCTACCTAC
TTTGCTGCTTTTCTTGTTTGGTGTTTTCTTCCTAGCATTTGCAAAGAAAGAAATTTCTATTATTTCAACTGCAACAGTTG
AACCAAATATAATTCTTTCCAATATTCAATCTACAAGTAATAATACAATATTAACCAATAATCTAAAAGATAATAAATAT
GTCAAATTTGGAGACTTATTGATAAAATATGATTCAAGAAAAGAAGGTATTCAACAAGAGACCTATCAAACTCAATTAAA
TAATTTACAAATCCAAAAAGAACAGTTAGAGCTATTAAAAGCAAGTATTGAAGCTGGAAACAGTCAATTTCCAGAAAAAG
ATAATTATGGATATTATCAAACATTTATTGACTACTTAAATCAGATAAACACCTTATCAGCCAATGTAAATCAGCAAAAT
GAAAATGTCTCTTCACAAAATACTGCAGCTAGCAATCAGCAAGTAGAAATTGAGAATGCCATCAAAGGTCTCACAAGTCA
AATTTCAGATTATCAATCTGTTCGCTCGGCGATTCAAAATGGAACAGTGGTAGATCTTGATAATCGGGCTTATTCTATCT
ATAGGAGTTATCTAACTCAAACATCGAGTTTGGTAGATAATACTGATAAAACCGCTGTTATTAATCAATTTGTTGCTCAA
ATTGATAGTCAGATCAATCAACTAGAGAGTAGTGTAGCTGGTTATCGGATTCAGCATGCTGGTTCAGGAGTGCAACAATC
TTACTCTTCAACTCTAGAGAGTCAACTGGCTTCCTTAAAAGCGCAAAGCATAACCAAAGTTGAGCAAGAGTTGTCTGCTT
TGTCGAATCAAATTACAGAATTAGAGGGAACAAATAAACTTCAGAAGAACACATCATCTAAGACCTCTATAGTTGCCAAT
GAAGATGGTGTGTTGCATCTTAATCAGGAATTTATTGGTGCAAATATTGTTCCTGAAGGAACAATATTTGCTCAAGTTTA
TCCAGAAATGAAAAAAGGAACTGTTGTAAAAATCACAGGTTATTTACCTTCGACGGAAATATCAAGTATTTCTATTGGAG
ATACAGCACGATTTTCCACGAAAGATGATAATGGCGAAACTCTTGATTTAATAGTTAAATTATCTAGTATTGACAATGCT
GCAACTAAAACAAAAAATGGGAATTATTTTAAAGTTGAATCTAAGTTACAGCTTAAAGAAAAAGAAGCTCAATTATTGAA
ATATGGGCTTGAGGGTAAATTTATTTTAATTACGGGAACAAAAAGTTACTTGAATTACTATATTGATAAATTTATCGGTG
AGAAGTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(317-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

50

99.341

0.497
  comB Streptococcus pneumoniae D39

50

99.341

0.497
  comB Streptococcus pneumoniae R6

50

99.341

0.497
  comB Streptococcus pneumoniae TIGR4

49.115

99.341

0.488
  comB Streptococcus mitis NCTC 12261

48.673

99.341

0.484
  comB Streptococcus mitis SK321

48.451

99.341

0.481
  comB Streptococcus gordonii str. Challis substr. CH1

48.115

99.121

0.477