Detailed information NTG0506494

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: I2435_RS05705
• Genome accession: NZ_CP065059
• Coordinates: 1136969..1137643 (-)
• Length: 224 a.a.
• NCBI ID: WP_043983576.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ25
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1131969..1142643

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2435_RS05665 (JFMEOBDD_01142)	-	1132765..1133145 (-)	381	WP_043029682.1	hypothetical protein	-
I2435_RS05670 (JFMEOBDD_01143)	-	1133320..1133571 (-)	252	WP_043029681.1	hypothetical protein	-
I2435_RS05675 (JFMEOBDD_01144)	-	1133573..1133956 (-)	384	WP_012678013.1	hypothetical protein	-
I2435_RS05680 (JFMEOBDD_01145)	-	1133880..1134170 (-)	291	WP_014622816.1	hypothetical protein	-
I2435_RS05685 (JFMEOBDD_01146)	-	1134180..1134584 (-)	405	WP_012678014.1	hypothetical protein	-
I2435_RS05690 (JFMEOBDD_01147)	-	1134603..1134848 (-)	246	WP_043030765.1	hypothetical protein	-
I2435_RS05695 (JFMEOBDD_01148)	-	1134849..1135283 (-)	435	WP_043030769.1	hypothetical protein	-
I2435_RS05700 (JFMEOBDD_01149)	ciaH	1135666..1136976 (-)	1311	WP_159334696.1	HAMP domain-containing sensor histidine kinase	Regulator
I2435_RS05705 (JFMEOBDD_01150)	ciaR	1136969..1137643 (-)	675	WP_043983576.1	response regulator transcription factor	Regulator
I2435_RS05710 (JFMEOBDD_01151)	-	1138070..1140607 (-)	2538	WP_206156280.1	M1 family metallopeptidase	-
I2435_RS05715 (JFMEOBDD_01152)	phoU	1140837..1141490 (-)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
I2435_RS05720 (JFMEOBDD_01153)	pstB	1141561..1142319 (-)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25527.50 Da
• Isoelectric Point: 4.5644

>NTDB_id=506494 I2435_RS05705 WP_043983576.1 1136969..1137643(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLVY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=506494 I2435_RS05705 WP_043983576.1 1136969..1137643(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTGTCAAATTCTATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACGCAGGTTTTTGATGGTGACGAAGGACTCTATGAGGCAGAAAGCGGTATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGTTAAAAGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATCGATGACAAAGGGCATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAAGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGACAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGCCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAGTCTAT
ATTCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	85.068	98.661	0.839
ciaR	Streptococcus pneumoniae Rx1	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae D39	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae R6	80.995	98.661	0.799
ciaR	Streptococcus pneumoniae TIGR4	80.995	98.661	0.799
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.428	100	0.393
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.362