Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I2435_RS05700 Genome accession   NZ_CP065059
Coordinates   1135666..1136976 (-) Length   436 a.a.
NCBI ID   WP_159334696.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ25     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1130666..1141976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2435_RS05650 (JFMEOBDD_01139) - 1130868..1131152 (-) 285 WP_012677440.1 hypothetical protein -
  I2435_RS05655 (JFMEOBDD_01140) - 1131171..1131563 (-) 393 WP_043039395.1 hypothetical protein -
  I2435_RS05660 (JFMEOBDD_01141) - 1131560..1132768 (-) 1209 WP_206156279.1 hypothetical protein -
  I2435_RS05665 (JFMEOBDD_01142) - 1132765..1133145 (-) 381 WP_043029682.1 hypothetical protein -
  I2435_RS05670 (JFMEOBDD_01143) - 1133320..1133571 (-) 252 WP_043029681.1 hypothetical protein -
  I2435_RS05675 (JFMEOBDD_01144) - 1133573..1133956 (-) 384 WP_012678013.1 hypothetical protein -
  I2435_RS05680 (JFMEOBDD_01145) - 1133880..1134170 (-) 291 WP_014622816.1 hypothetical protein -
  I2435_RS05685 (JFMEOBDD_01146) - 1134180..1134584 (-) 405 WP_012678014.1 hypothetical protein -
  I2435_RS05690 (JFMEOBDD_01147) - 1134603..1134848 (-) 246 WP_043030765.1 hypothetical protein -
  I2435_RS05695 (JFMEOBDD_01148) - 1134849..1135283 (-) 435 WP_043030769.1 hypothetical protein -
  I2435_RS05700 (JFMEOBDD_01149) ciaH 1135666..1136976 (-) 1311 WP_159334696.1 HAMP domain-containing sensor histidine kinase Regulator
  I2435_RS05705 (JFMEOBDD_01150) ciaR 1136969..1137643 (-) 675 WP_043983576.1 response regulator transcription factor Regulator
  I2435_RS05710 (JFMEOBDD_01151) - 1138070..1140607 (-) 2538 WP_206156280.1 M1 family metallopeptidase -
  I2435_RS05715 (JFMEOBDD_01152) phoU 1140837..1141490 (-) 654 WP_012678018.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49736.38 Da        Isoelectric Point: 9.5602

>NTDB_id=506493 I2435_RS05700 WP_159334696.1 1135666..1136976(-) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MNKLKKELLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLRQLMTILFDNAIKYTDHNGMVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=506493 I2435_RS05700 WP_159334696.1 1135666..1136976(-) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGAATAAACTAAAAAAAGAATTATTGTCCGATAATTATACACATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCTAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACCACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTTCACATTAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAGCTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACCACTAATTTGTTAAACCTAGCGAGACGTGATGATGGGATCAAGCCGCAGCTGGTTGATGTTG
ATGCAGCATTTTTTGACACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTACTCAGGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGACCATAACGGTATGGTTGAGGTCAAGGTTAGAACGACTGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGTACCATATTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.666

100

0.578
  ciaH Streptococcus pneumoniae Rx1

51.376

100

0.514
  ciaH Streptococcus pneumoniae D39

51.376

100

0.514
  ciaH Streptococcus pneumoniae R6

51.376

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.376

100

0.514