Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   I2435_RS03415 Genome accession   NZ_CP065059
Coordinates   653586..654296 (+) Length   236 a.a.
NCBI ID   WP_012515994.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ25     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 648586..659296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2435_RS03390 - 649122..649281 (+) 160 Protein_615 aquaporin -
  I2435_RS03395 (JFMEOBDD_00679) - 649413..649952 (+) 540 WP_206156667.1 hypothetical protein -
  I2435_RS03400 (JFMEOBDD_00680) - 649949..651064 (+) 1116 WP_206156669.1 acetyl-CoA C-acyltransferase -
  I2435_RS03405 (JFMEOBDD_00681) - 651054..652316 (+) 1263 WP_206156670.1 AMP-binding protein -
  I2435_RS03410 (JFMEOBDD_00682) - 652361..653377 (+) 1017 WP_206156672.1 DUF3114 domain-containing protein -
  I2435_RS03415 (JFMEOBDD_00683) vicR 653586..654296 (+) 711 WP_012515994.1 response regulator YycF Regulator
  I2435_RS03420 (JFMEOBDD_00684) vicK 654289..655641 (+) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2435_RS03425 (JFMEOBDD_00685) vicX 655645..656454 (+) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2435_RS03430 (JFMEOBDD_00686) - 656645..658387 (+) 1743 WP_012677638.1 restriction endonuclease FokI C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 26981.84 Da        Isoelectric Point: 4.9038

>NTDB_id=506485 I2435_RS03415 WP_012515994.1 653586..654296(+) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=506485 I2435_RS03415 WP_012515994.1 653586..654296(+) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCCTTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAAGCCAGATTTGATTATTTTGGATTTGA
TGCTTCCTGAGCTAGATGGTCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGCCTTGAAATAGGGGCCGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTAACCATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377