Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I2435_RS03420 Genome accession   NZ_CP065059
Coordinates   654289..655641 (+) Length   450 a.a.
NCBI ID   WP_012677636.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ25     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 649289..660641
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2435_RS03395 (JFMEOBDD_00679) - 649413..649952 (+) 540 WP_206156667.1 hypothetical protein -
  I2435_RS03400 (JFMEOBDD_00680) - 649949..651064 (+) 1116 WP_206156669.1 acetyl-CoA C-acyltransferase -
  I2435_RS03405 (JFMEOBDD_00681) - 651054..652316 (+) 1263 WP_206156670.1 AMP-binding protein -
  I2435_RS03410 (JFMEOBDD_00682) - 652361..653377 (+) 1017 WP_206156672.1 DUF3114 domain-containing protein -
  I2435_RS03415 (JFMEOBDD_00683) vicR 653586..654296 (+) 711 WP_012515994.1 response regulator YycF Regulator
  I2435_RS03420 (JFMEOBDD_00684) vicK 654289..655641 (+) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2435_RS03425 (JFMEOBDD_00685) vicX 655645..656454 (+) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2435_RS03430 (JFMEOBDD_00686) - 656645..658387 (+) 1743 WP_012677638.1 restriction endonuclease FokI C-terminal domain-containing protein -
  I2435_RS03435 (JFMEOBDD_00687) - 658408..660339 (-) 1932 WP_206156674.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51541.94 Da        Isoelectric Point: 5.5557

>NTDB_id=506486 I2435_RS03420 WP_012677636.1 654289..655641(+) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=506486 I2435_RS03420 WP_012677636.1 654289..655641(+) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCGCTGCGGCTGCGTTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACCAGTACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCTGA
TGGTGGGAAAATTATCGTAAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGATTGGGCATAC
CAAAGAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCGCAGGGGGGGACCGGC
TTAGGGCTGGCTATTGCCAAAGAAATTATCAAGCAGCACCGAGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631