Detailed information NTG0506482

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: I2435_RS02770
• Genome accession: NZ_CP065059
• Coordinates: 511060..513216 (-)
• Length: 718 a.a.
• NCBI ID: WP_165627811.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ25
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 506060..518216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2435_RS02740 (JFMEOBDD_00548)	-	506153..506410 (+)	258	WP_043030068.1	Blp family class II bacteriocin	-
I2435_RS02745 (JFMEOBDD_00549)	-	506427..506621 (+)	195	WP_038674052.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I2435_RS02750 (JFMEOBDD_00550)	comE/blpR	507255..508004 (+)	750	WP_111690344.1	response regulator transcription factor	Regulator
I2435_RS10155	-	508508..509338 (+)	831	WP_228269594.1	GHKL domain-containing protein	-
I2435_RS02760 (JFMEOBDD_00552)	-	509457..509591 (-)	135	WP_012516117.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
I2435_RS02765 (JFMEOBDD_00553)	-	509691..511049 (-)	1359	WP_206156617.1	bacteriocin secretion accessory protein	-
I2435_RS02770 (JFMEOBDD_00554)	comA/nlmT	511060..513216 (-)	2157	WP_165627811.1	peptide cleavage/export ABC transporter	Regulator
I2435_RS02775 (JFMEOBDD_00555)	-	513474..513722 (+)	249	WP_012677516.1	garvicin Q family class II bacteriocin	-
I2435_RS02780 (JFMEOBDD_00556)	-	513729..514025 (+)	297	WP_012516113.1	bacteriocin immunity protein	-
I2435_RS02785 (JFMEOBDD_00557)	-	514755..514973 (+)	219	WP_206156618.1	leucocin A/sakacin P family class II bacteriocin	-
I2435_RS02790 (JFMEOBDD_00558)	-	514973..515269 (+)	297	WP_043031276.1	bacteriocin immunity protein	-
I2435_RS02795 (JFMEOBDD_00559)	-	515421..515675 (+)	255	WP_165622963.1	Blp family class II bacteriocin	-
I2435_RS02800 (JFMEOBDD_00560)	-	515692..515895 (+)	204	WP_012516109.1	Blp family class II bacteriocin	-
I2435_RS02805 (JFMEOBDD_00561)	-	516556..516969 (+)	414	WP_021321055.1	hypothetical protein	-
I2435_RS02810 (JFMEOBDD_00562)	-	517220..517801 (+)	582	WP_165627810.1	GNAT family N-acetyltransferase	-
I2435_RS02815 (JFMEOBDD_00563)	-	517954..518142 (-)	189	Protein_500	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 80690.80 Da
• Isoelectric Point: 7.7851

>NTDB_id=506482 I2435_RS02770 WP_165627811.1 511060..513216(-) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MTLFYRRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEIGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPNPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSFFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide

• Length: 2157 bp

>NTDB_id=506482 I2435_RS02770 WP_165627811.1 511060..513216(-) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGACACTTTTTTATAGAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCCTCAATCGC
AAGATATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCTCTTG
GTATTGTTATGGCTGCTAAGGAAATAGGGTTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATTGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCAATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCAGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAACCCTTATATTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTGCTGGTTC
ATACTATCTCCAGGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCTTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATCCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCTATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTCGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATTGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAATAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAACGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGATTGTTGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-439)

• ABC transporter (ABC_tran) (501-650)

• Peptidase C39 family (Peptidase_C39) (8-143)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.572	99.861	0.705
comA	Streptococcus mitis SK321	67.321	99.304	0.669
comA	Streptococcus mitis NCTC 12261	67.041	99.304	0.666
comA	Streptococcus pneumoniae Rx1	66.62	99.304	0.662
comA	Streptococcus pneumoniae D39	66.62	99.304	0.662
comA	Streptococcus pneumoniae R6	66.62	99.304	0.662
comA	Streptococcus pneumoniae TIGR4	66.339	99.304	0.659
comA	Streptococcus gordonii str. Challis substr. CH1	64.797	99.304	0.643