Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   I2435_RS02750 Genome accession   NZ_CP065059
Coordinates   507255..508004 (+) Length   249 a.a.
NCBI ID   WP_111690344.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ25     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 502255..513004
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2435_RS10150 (JFMEOBDD_00544) - 502823..503110 (+) 288 WP_011106694.1 hypothetical protein -
  I2435_RS02725 (JFMEOBDD_00545) prx 503178..503360 (+) 183 WP_206156615.1 Paratox Regulator
  I2435_RS02730 (JFMEOBDD_00546) - 503500..504468 (+) 969 WP_206156616.1 DNA-binding protein -
  I2435_RS02735 (JFMEOBDD_00547) rlmD 504465..505832 (+) 1368 WP_165627812.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  I2435_RS02740 (JFMEOBDD_00548) - 506153..506410 (+) 258 WP_043030068.1 Blp family class II bacteriocin -
  I2435_RS02745 (JFMEOBDD_00549) - 506427..506621 (+) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I2435_RS02750 (JFMEOBDD_00550) comE/blpR 507255..508004 (+) 750 WP_111690344.1 response regulator transcription factor Regulator
  I2435_RS10155 - 508508..509338 (+) 831 WP_228269594.1 GHKL domain-containing protein -
  I2435_RS02760 (JFMEOBDD_00552) - 509457..509591 (-) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I2435_RS02765 (JFMEOBDD_00553) - 509691..511049 (-) 1359 WP_206156617.1 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29217.65 Da        Isoelectric Point: 8.4602

>NTDB_id=506481 I2435_RS02750 WP_111690344.1 507255..508004(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRSHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLHRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=506481 I2435_RS02750 WP_111690344.1 507255..508004(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAGCAGAGATATTTAGAAAAGCTCATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGACTGTTTTGGAAGGTCTCACCAGCTATTAAGTGCTATCAAGAAGAACTGTGGTCAGC
AGCTATTTTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTACATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

100

0.522
  comE/comE1 Streptococcus equinus JB1

40.586

95.984

0.39
  comE/comE2 Streptococcus equinus JB1

36.29

99.598

0.361