Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I2434_RS04600 Genome accession   NZ_CP065058
Coordinates   977026..977700 (+) Length   224 a.a.
NCBI ID   WP_043983576.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 972026..982700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS04585 (MCPGFBBE_00909) pstB 972346..973104 (+) 759 WP_012678019.1 phosphate ABC transporter ATP-binding protein PstB -
  I2434_RS04590 (MCPGFBBE_00910) phoU 973175..973828 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  I2434_RS04595 (MCPGFBBE_00911) - 974062..976599 (+) 2538 WP_043052123.1 M1 family metallopeptidase -
  I2434_RS04600 (MCPGFBBE_00912) ciaR 977026..977700 (+) 675 WP_043983576.1 response regulator transcription factor Regulator
  I2434_RS04605 (MCPGFBBE_00913) ciaH 977693..979003 (+) 1311 WP_165623301.1 HAMP domain-containing sensor histidine kinase Regulator
  I2434_RS04610 (MCPGFBBE_00914) - 979386..979769 (+) 384 WP_206157680.1 hypothetical protein -
  I2434_RS04615 (MCPGFBBE_00915) - 979770..980963 (+) 1194 WP_024273226.1 lipase -
  I2434_RS04620 (MCPGFBBE_00916) - 980960..981352 (+) 393 WP_042670596.1 hypothetical protein -
  I2434_RS04625 (MCPGFBBE_00917) - 981371..981655 (+) 285 WP_042670597.1 hypothetical protein -
  I2434_RS04630 (MCPGFBBE_00918) rpsT 981868..982116 (-) 249 WP_012678006.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25527.50 Da        Isoelectric Point: 4.5644

>NTDB_id=506422 I2434_RS04600 WP_043983576.1 977026..977700(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLVY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=506422 I2434_RS04600 WP_043983576.1 977026..977700(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTGTCAAATTCTATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACGCAGGTTTTTGATGGTGACGAAGGACTCTATGAGGCAGAAAGCGGTATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGTTAAAAGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATCGATGACAAAGGGCATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAAGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGACAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGCCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAGTCTAT
ATTCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

85.068

98.661

0.839
  ciaR Streptococcus pneumoniae Rx1

80.995

98.661

0.799
  ciaR Streptococcus pneumoniae D39

80.995

98.661

0.799
  ciaR Streptococcus pneumoniae R6

80.995

98.661

0.799
  ciaR Streptococcus pneumoniae TIGR4

80.995

98.661

0.799
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.428

100

0.393
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.362