Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I2434_RS04605 Genome accession   NZ_CP065058
Coordinates   977693..979003 (+) Length   436 a.a.
NCBI ID   WP_165623301.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 972693..984003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS04590 (MCPGFBBE_00910) phoU 973175..973828 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  I2434_RS04595 (MCPGFBBE_00911) - 974062..976599 (+) 2538 WP_043052123.1 M1 family metallopeptidase -
  I2434_RS04600 (MCPGFBBE_00912) ciaR 977026..977700 (+) 675 WP_043983576.1 response regulator transcription factor Regulator
  I2434_RS04605 (MCPGFBBE_00913) ciaH 977693..979003 (+) 1311 WP_165623301.1 HAMP domain-containing sensor histidine kinase Regulator
  I2434_RS04610 (MCPGFBBE_00914) - 979386..979769 (+) 384 WP_206157680.1 hypothetical protein -
  I2434_RS04615 (MCPGFBBE_00915) - 979770..980963 (+) 1194 WP_024273226.1 lipase -
  I2434_RS04620 (MCPGFBBE_00916) - 980960..981352 (+) 393 WP_042670596.1 hypothetical protein -
  I2434_RS04625 (MCPGFBBE_00917) - 981371..981655 (+) 285 WP_042670597.1 hypothetical protein -
  I2434_RS04630 (MCPGFBBE_00918) rpsT 981868..982116 (-) 249 WP_012678006.1 30S ribosomal protein S20 -
  I2434_RS04635 (MCPGFBBE_00919) coaA 982170..983090 (-) 921 WP_014622823.1 type I pantothenate kinase -
  I2434_RS04640 (MCPGFBBE_00920) - 983357..983953 (+) 597 WP_021320719.1 methyltransferase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49676.30 Da        Isoelectric Point: 9.5548

>NTDB_id=506423 I2434_RS04605 WP_165623301.1 977693..979003(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MNKLKKELLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=506423 I2434_RS04605 WP_165623301.1 977693..979003(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGAATAAACTAAAAAAAGAATTATTGTCCGATAATTATACACATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCTAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACCACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTCCACATCAAAAATTAT
CCGGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAGCTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCCAGACGTGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAGTCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGTACCATATTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.606

100

0.516
  ciaH Streptococcus pneumoniae D39

51.606

100

0.516
  ciaH Streptococcus pneumoniae R6

51.606

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.606

100

0.516