Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   I2434_RS02645 Genome accession   NZ_CP065058
Coordinates   545657..547024 (+) Length   455 a.a.
NCBI ID   WP_012515170.1    Uniprot ID   A0AAW3GNZ0
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 540735..551871 545657..547024 within 0


Gene organization within MGE regions


Location: 540735..551871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS02615 (MCPGFBBE_00519) - 540735..541994 (-) 1260 WP_111677636.1 ISL3-like element ISSeq1 family transposase -
  I2434_RS02620 (MCPGFBBE_00521) - 542501..542641 (+) 141 WP_012515166.1 hypothetical protein -
  I2434_RS02625 (MCPGFBBE_00522) - 542754..542912 (+) 159 WP_021320463.1 hypothetical protein -
  I2434_RS02630 (MCPGFBBE_00523) - 542926..543072 (+) 147 WP_021320464.1 hypothetical protein -
  I2434_RS02635 (MCPGFBBE_00524) - 543095..543262 (+) 168 WP_012515168.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I2434_RS02640 (MCPGFBBE_00525) comA 543489..545642 (+) 2154 WP_165623590.1 peptide cleavage/export ABC transporter ComA Regulator
  I2434_RS02645 (MCPGFBBE_00526) comB 545657..547024 (+) 1368 WP_012515170.1 bacteriocin secretion accessory protein Regulator
  I2434_RS02650 (MCPGFBBE_00527) - 547533..547769 (+) 237 WP_024273149.1 hypothetical protein -
  I2434_RS02655 (MCPGFBBE_00528) nrdF 548226..549239 (+) 1014 WP_043040212.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
  I2434_RS02660 (MCPGFBBE_00529) nrdI 549241..549651 (+) 411 WP_043052823.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  I2434_RS02665 (MCPGFBBE_00530) nrdE 549697..551871 (+) 2175 WP_021320467.1 class 1b ribonucleoside-diphosphate reductase subunit alpha -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50812.92 Da        Isoelectric Point: 5.1918

>NTDB_id=506414 I2434_RS02645 WP_012515170.1 545657..547024(+) (comB) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MNNNILESAEFYNRRYHNFSSRVILPTLLLFLFGVFFLAFAKKEISIISTATVEPNIILSNIQSTSNNTILTNNLKDNKY
VKFGDLLIKYDSRKEGIQQETYQTQLNNLQIQKEQLELLKASIEAGNSQFPEKDNYGYYQTFIDYLNQINTLSANVNQQN
ENVSSQNTAASNQQVEIENAIKGLTSQISDYQSVRSAIQNGTVVDLDNRAYSIYRSYLTQTSSLVDNTDKTAVINQFVAQ
IDSQINQLESSVAGYRIQHAGSGVQQSYSSTLESQLASLKAQSITKVEQELSALSNQITELEGTNKLQKNTSSKTSIVAN
EDGVLHLNQEFIGANIVPEGTIFAQVYPEMKKGTVVKITGYLPSTEISSISIGDTARFSTKDDNGETLDLIVKLSSIDNA
ATKTKNGNYFKVESKLQLKEKEAQLLKYGLEGKFILITGTKSYLNYYIDKFIGEK

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=506414 I2434_RS02645 WP_012515170.1 545657..547024(+) (comB) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGAATAACAATATATTAGAAAGTGCGGAATTTTATAACCGTCGTTACCACAACTTTTCTAGTCGTGTCATTCTACCTAC
TTTGCTGCTTTTCTTGTTTGGTGTTTTCTTCCTAGCATTTGCAAAGAAAGAAATTTCTATTATTTCAACTGCAACAGTTG
AACCAAATATAATTCTTTCCAATATTCAATCTACAAGTAATAATACAATATTAACCAATAATCTAAAAGATAATAAATAT
GTCAAATTTGGAGACTTATTGATAAAATATGATTCAAGAAAAGAAGGTATTCAACAAGAGACCTATCAAACTCAATTAAA
TAATTTACAAATCCAAAAAGAACAGTTAGAGCTATTAAAAGCAAGTATTGAAGCTGGAAACAGTCAATTTCCAGAAAAAG
ATAATTATGGATATTATCAAACATTTATTGACTACTTAAATCAGATAAACACTTTATCAGCCAATGTAAATCAGCAAAAT
GAAAATGTCTCTTCACAAAATACTGCAGCTAGCAATCAGCAAGTAGAAATTGAGAATGCCATCAAAGGTCTCACAAGTCA
AATTTCAGATTATCAATCTGTTCGCTCGGCGATTCAAAATGGAACAGTGGTAGATCTTGATAATCGGGCTTATTCTATCT
ATAGGAGTTATCTAACTCAAACATCGAGTTTGGTAGATAATACTGATAAAACCGCTGTTATTAATCAATTTGTTGCTCAA
ATTGATAGTCAGATCAATCAACTAGAGAGTAGTGTAGCTGGTTATCGGATTCAGCATGCTGGTTCAGGAGTGCAACAATC
TTACTCTTCAACTCTAGAGAGTCAACTGGCTTCCTTAAAAGCGCAAAGCATAACCAAAGTTGAGCAAGAGTTGTCTGCTT
TGTCGAATCAAATTACAGAATTAGAGGGAACAAATAAACTTCAGAAGAACACATCATCTAAGACCTCTATAGTTGCCAAT
GAAGATGGTGTGTTGCATCTTAATCAGGAATTTATTGGTGCAAATATTGTTCCTGAAGGAACAATATTTGCTCAAGTTTA
TCCAGAAATGAAAAAAGGAACTGTTGTAAAAATCACAGGTTATTTACCTTCGACGGAAATATCAAGTATTTCTATTGGAG
ATACAGCACGATTTTCCACGAAAGATGATAATGGCGAAACTCTTGATTTAATAGTTAAATTATCTAGTATTGACAATGCT
GCAACTAAAACAAAAAATGGGAATTATTTTAAAGTTGAATCTAAGTTACAGCTTAAAGAAAAAGAAGCTCAATTATTGAA
ATATGGGCTTGAGGGTAAATTTATTTTAATTACGGGAACAAAAAGTTACTTGAATTACTATATTGATAAATTTATCGGTG
AGAAGTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(317-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

50.221

99.341

0.499
  comB Streptococcus pneumoniae D39

50.221

99.341

0.499
  comB Streptococcus pneumoniae R6

50.221

99.341

0.499
  comB Streptococcus pneumoniae TIGR4

49.336

99.341

0.49
  comB Streptococcus mitis NCTC 12261

49.115

99.341

0.488
  comB Streptococcus mitis SK321

48.894

99.341

0.486
  comB Streptococcus gordonii str. Challis substr. CH1

47.894

99.121

0.475