Detailed information NTG0506397

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: I2434_RS00290
• Genome accession: NZ_CP065058
• Coordinates: 50013..50927 (+)
• Length: 304 a.a.
• NCBI ID: WP_165623357.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ18
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 45013..55927

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2434_RS00265 (MCPGFBBE_00053)	purE	45494..45982 (+)	489	WP_021320238.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
I2434_RS00270 (MCPGFBBE_00054)	purK	45969..47042 (+)	1074	WP_043038328.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
I2434_RS00275 (MCPGFBBE_00055)	-	47057..47278 (+)	222	WP_043024883.1	hypothetical protein	-
I2434_RS00280 (MCPGFBBE_00056)	-	47330..48403 (+)	1074	WP_043024885.1	YaaC family protein	-
I2434_RS00285 (MCPGFBBE_00057)	purB	48422..49714 (+)	1293	WP_165623356.1	adenylosuccinate lyase	-
I2434_RS00290 (MCPGFBBE_00058)	comR	50013..50927 (+)	915	WP_165623357.1	XRE family transcriptional regulator	Regulator
I2434_RS00300 (MCPGFBBE_00060)	ruvB	51142..52143 (+)	1002	WP_165623358.1	Holliday junction branch migration DNA helicase RuvB	-
I2434_RS00305 (MCPGFBBE_00061)	-	52437..52895 (+)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
I2434_RS00310 (MCPGFBBE_00062)	-	52901..53302 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
I2434_RS00315 (MCPGFBBE_00063)	-	53299..55080 (+)	1782	WP_111721605.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35795.36 Da
• Isoelectric Point: 4.5517

>NTDB_id=506397 I2434_RS00290 WP_165623357.1 50013..50927(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKSNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=506397 I2434_RS00290 WP_165623357.1 50013..50927(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGATTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGACATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAGCAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTCAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.724	95.395	0.493
comR	Streptococcus mutans UA159	49.498	98.355	0.487
comR	Streptococcus suis P1/7	38.591	98.026	0.378
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis D9	37.037	97.697	0.362