Detailed information NTG0506395

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: I2433_RS10380
• Genome accession: NZ_CP065056
• Coordinates: 2145242..2146465 (+)
• Length: 407 a.a.
• NCBI ID: WP_012516520.1
• Uniprot ID: A0AAW3GJZ4
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ14
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2140242..2151465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2433_RS10365 (JDBNIEOD_02085)	-	2142626..2144023 (-)	1398	WP_206152266.1	ISNCY-like element ISSeq2 family transposase	-
I2433_RS10375 (JDBNIEOD_02087)	rlmH	2144553..2145032 (-)	480	WP_154804261.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
I2433_RS10380 (JDBNIEOD_02088)	htrA	2145242..2146465 (+)	1224	WP_012516520.1	trypsin-like peptidase domain-containing protein	Regulator
I2433_RS10385 (JDBNIEOD_02089)	spo0J	2146590..2147363 (+)	774	WP_206152267.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42434.01 Da
• Isoelectric Point: 5.4809

>NTDB_id=506395 I2433_RS10380 WP_012516520.1 2145242..2146465(+) (htrA) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGATTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAAS
PAISNPYINLFGEENDTSAVQKEDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVTSRNEAGETISTNAIQTDAAINP
GNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGIGFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQ
LNIPTSVTSGVVVASTQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKVDIKLTKTT
KDLTKKQ

Nucleotide

• Length: 1224 bp

>NTDB_id=506395 I2433_RS10380 WP_012516520.1 2145242..2146465(+) (htrA) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
GTGTTAAAATCAAAAAATATATTGAAGCCCTTATGGGTTTTAGCCATTGGATTTTTAGGGGGCTTATTAGCTGCCTTAGT
TGTTAATGGATTTAGTCAGAATTCTCTAACATCTTCAAATGCAAAGGGAGCAACGACAACAAGCAACGTCAGCTTTAACA
ATACAACTGATACAACAAAGGCTGTTAAGGTGGTTCAAGATGCTGTAGTGTCTGTTATTAACTATCAAAAGGCTGCTTCG
CCTGCCATTTCAAATCCTTACATCAATCTTTTCGGAGAAGAAAATGATACCTCAGCAGTACAAAAAGAGGACGAGCTAAG
CATACACAGTGAAGGCTCGGGTGTTGTCTACAAAAAAGAAGGAAATACTGCTTATCTTGTAACCAACAATCATGTTATTG
AGGGAGCTCAACGAATTGAAATTTTAACAGCAGACGGCTCTAAGATCGTTGGAGAACTAGTTGGTGCAGACACTTATTCT
GACCTAGCTGTTGTCAAAGTTGCTGCTGATAAAATCAAAACAATAGCCAAATTTGCAGATTCAACCAAAATTAATGTTGG
AGAGGTAGCCATTGCAATTGGTAGTCCTCTTGGAACAAAATATGCCAACTCAGTGACAGAAGGGATTGTTTCAAGTCTAA
GCCGTACAGTCACTTCAAGAAATGAAGCAGGTGAGACCATCTCAACAAATGCTATCCAAACTGATGCTGCTATCAATCCA
GGTAATTCAGGTGGACCACTCATCAATATTGAAGGTCAGGTCATTGGTATCAACTCAAGTAAAATATCCTCAACACCTAC
TGGTAGCGGCGGAGCCATTGAGGGAATTGGCTTTGCTATCCCATCAAGCGATGTTGTCACCATTATTAACCAACTAGAGT
CTAACGGAGCTGTTATCAGACCAGCCTTAGGCATTACAATGGTAAACTTAAGTAATCTATCAACCAATGCATTGATTCAA
TTGAATATTCCAACAAGCGTTACCAGCGGTGTTGTCGTAGCCTCTACTCAAGATGGCATGCCTGCTCTTGGTAAATTGGA
GCAGTATGATGTCATTACTGAGGTTGACGGTAAAGAAGTCAGCTCAATTAGTGACCTACAAAGTGTCTTATATAGTCATG
AGATTAACGACACCATTAAGGTAACCTTCTACAGAGGAACTGCTAAGAAGAAAGTTGACATCAAATTAACAAAAACAACT
AAGGATCTAACTAAAAAGCAGTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (112-257)

• PDZ domain (PDZ_2) (301-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.275	100	0.614
htrA	Streptococcus gordonii str. Challis substr. CH1	57.855	98.526	0.57
htrA	Streptococcus mitis NCTC 12261	54.66	97.543	0.533
htrA	Streptococcus pneumoniae Rx1	53.634	98.034	0.526
htrA	Streptococcus pneumoniae D39	53.634	98.034	0.526
htrA	Streptococcus pneumoniae R6	53.634	98.034	0.526
htrA	Streptococcus pneumoniae TIGR4	53.634	98.034	0.526