Detailed information NTG0506372

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: I2433_RS05245
• Genome accession: NZ_CP065056
• Coordinates: 1078844..1079581 (-)
• Length: 245 a.a.
• NCBI ID: WP_165622997.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ14
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1073844..1084581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2433_RS05220 (JDBNIEOD_01044)	-	1074544..1074825 (-)	282	WP_012515598.1	lactococcin 972 family bacteriocin	-
I2433_RS05225 (JDBNIEOD_01045)	-	1075683..1075913 (-)	231	WP_206151885.1	Blp family class II bacteriocin	-
I2433_RS05230 (JDBNIEOD_01046)	-	1076177..1077340 (-)	1164	WP_043030788.1	ABC transporter permease subunit	-
I2433_RS05235 (JDBNIEOD_01047)	-	1077346..1078200 (-)	855	Protein_969	ABC transporter ATP-binding protein	-
I2433_RS05240	-	1078267..1078472 (-)	206	Protein_970	ComC/BlpC family leader-containing pheromone/bacteriocin	-
I2433_RS05245 (JDBNIEOD_01049)	comE/blpR	1078844..1079581 (-)	738	WP_165622997.1	response regulator transcription factor	Regulator
I2433_RS05250 (JDBNIEOD_01050)	-	1080344..1080649 (-)	306	WP_012515590.1	hypothetical protein	-
I2433_RS05255 (JDBNIEOD_01051)	-	1080651..1080989 (-)	339	WP_012677982.1	cupin domain-containing protein	-
I2433_RS05260 (JDBNIEOD_01052)	-	1081017..1081772 (-)	756	WP_043038959.1	class I SAM-dependent methyltransferase	-
I2433_RS05265 (JDBNIEOD_01053)	-	1082032..1082487 (+)	456	WP_037578258.1	DUF1836 domain-containing protein	-
I2433_RS05270 (JDBNIEOD_01054)	-	1082471..1083121 (+)	651	WP_012515586.1	hemolysin III family protein	-
I2433_RS05275 (JDBNIEOD_01055)	-	1083231..1084136 (+)	906	WP_206151887.1	diacylglycerol kinase family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28868.25 Da
• Isoelectric Point: 7.8971

>NTDB_id=506372 I2433_RS05245 WP_165622997.1 1078844..1079581(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=506372 I2433_RS05245 WP_165622997.1 1078844..1079581(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAGCAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACCACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACCCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTACGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (18-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.719	98.776	0.531
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367