Detailed information NTG0506336

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: I2433_RS00280
• Genome accession: NZ_CP065056
• Coordinates: 47772..48686 (+)
• Length: 304 a.a.
• NCBI ID: WP_111692077.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ14
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42772..53686

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2433_RS00260 (JDBNIEOD_00052)	purE	43928..44416 (+)	489	WP_206152281.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
I2433_RS00265 (JDBNIEOD_00053)	purK	44403..45494 (+)	1092	WP_206152546.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
I2433_RS00270 (JDBNIEOD_00054)	-	45504..45728 (+)	225	WP_206152282.1	phosphoribosylaminoimidazole carboxylase	-
I2433_RS10690	-	45753..45824 (+)	72	Protein_34	hypothetical protein	-
I2433_RS00275 (JDBNIEOD_00055)	purB	46182..47474 (+)	1293	WP_206152283.1	adenylosuccinate lyase	-
I2433_RS00280 (JDBNIEOD_00056)	comR	47772..48686 (+)	915	WP_111692077.1	XRE family transcriptional regulator	Regulator
I2433_RS00290 (JDBNIEOD_00058)	ruvB	48901..49908 (+)	1008	WP_043039894.1	Holliday junction branch migration DNA helicase RuvB	-
I2433_RS00295 (JDBNIEOD_00059)	-	50149..50607 (+)	459	WP_206152284.1	low molecular weight protein-tyrosine-phosphatase	-
I2433_RS00300 (JDBNIEOD_00060)	-	50613..51014 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
I2433_RS00305 (JDBNIEOD_00061)	-	51011..52792 (+)	1782	WP_043029239.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35790.34 Da
• Isoelectric Point: 4.5517

>NTDB_id=506336 I2433_RS00280 WP_111692077.1 47772..48686(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIAGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKPEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=506336 I2433_RS00280 WP_111692077.1 47772..48686(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTGCGGTATCAGAAGAAGATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAGTTATCCATCCGTCAATTAGCACGAATAGAATTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAACTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGATTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAGCAAACAAAAAGTAAGACTCAATTTAGAGAGAATGAT
CTCATTCTTATTGAGCTGTATTTAGCGTACCTCGACATTGCAGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTGTTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATTGTCAATAAAATAGCTATAG
GAATTTCCTCGTTGAGCATCAAAAACAATAAGCCGGAGATTCTTGAGAAGGTTATTGTACTTAGTCAAAAAATTATCCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATATGCTCTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix domain (HTH_19) (6-69)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.587	99.671	0.743
comR	Streptococcus pyogenes MGAS315	54.817	99.013	0.543
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.069	95.395	0.497
comR	Streptococcus mutans UA159	49.164	98.355	0.484
comR	Streptococcus suis D9	37.542	99.013	0.372
comR	Streptococcus suis 05ZYH33	38.305	97.039	0.372
comR	Streptococcus suis P1/7	38.305	97.039	0.372