Detailed information NTG0506303

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: I2432_RS05150
• Genome accession: NZ_CP065054
• Coordinates: 1080198..1080872 (+)
• Length: 224 a.a.
• NCBI ID: WP_037578348.1
• Uniprot ID: A0A922NWP3
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ13
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1075198..1085872

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2432_RS05135 (LJFMMFNO_01025)	pstB	1075524..1076282 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
I2432_RS05140 (LJFMMFNO_01026)	phoU	1076353..1077006 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
I2432_RS05145 (LJFMMFNO_01027)	-	1077240..1079777 (+)	2538	WP_206158612.1	M1 family metallopeptidase	-
I2432_RS05150 (LJFMMFNO_01028)	ciaR	1080198..1080872 (+)	675	WP_037578348.1	response regulator transcription factor	Regulator
I2432_RS05155 (LJFMMFNO_01029)	ciaH	1080865..1082175 (+)	1311	WP_111678059.1	HAMP domain-containing sensor histidine kinase	Regulator
I2432_RS05160 (LJFMMFNO_01030)	-	1082559..1082987 (+)	429	WP_206158613.1	hypothetical protein	-
I2432_RS05165 (LJFMMFNO_01031)	-	1083214..1083609 (+)	396	WP_115250909.1	DUF1433 domain-containing protein	-
I2432_RS05170 (LJFMMFNO_01032)	-	1083609..1083854 (+)	246	WP_111678062.1	hypothetical protein	-
I2432_RS05175 (LJFMMFNO_01033)	-	1083873..1084271 (+)	399	WP_231871354.1	hypothetical protein	-
I2432_RS05180 (LJFMMFNO_01034)	-	1084274..1085467 (+)	1194	WP_249093119.1	hypothetical protein	-
I2432_RS05185 (LJFMMFNO_01035)	-	1085464..1085856 (+)	393	WP_165627640.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25555.55 Da
• Isoelectric Point: 4.5644

>NTDB_id=506303 I2432_RS05150 WP_037578348.1 1080198..1080872(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ13]
MIKILLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLVY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=506303 I2432_RS05150 WP_037578348.1 1080198..1080872(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ13]
ATGATAAAAATATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACGCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTAATGC
TGCCTGAAAAGGATGGCTTTCAGGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCTGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACTCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGTAAGGAGCTTGATTTACTAGTCTAT
ATTCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	81.448	98.661	0.804
ciaR	Streptococcus pneumoniae D39	81.448	98.661	0.804
ciaR	Streptococcus pneumoniae R6	81.448	98.661	0.804
ciaR	Streptococcus pneumoniae TIGR4	81.448	98.661	0.804
covR	Lactococcus lactis subsp. lactis strain DGCC12653	39.301	100	0.402
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.362