Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | I2432_RS00285 | Genome accession | NZ_CP065054 |
| Coordinates | 49149..50063 (+) | Length | 304 a.a. |
| NCBI ID | WP_115251528.1 | Uniprot ID | A0A380KQA4 |
| Organism | Streptococcus equi subsp. zooepidemicus strain SEZ13 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1510..68893 | 49149..50063 | within | 0 |
Gene organization within MGE regions
Location: 1510..68893
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I2432_RS00010 (LJFMMFNO_00002) | dnaN | 1510..2646 (+) | 1137 | WP_012677175.1 | DNA polymerase III subunit beta | - |
| I2432_RS00015 (LJFMMFNO_00003) | - | 2724..2921 (+) | 198 | WP_012514683.1 | DUF951 family protein | - |
| I2432_RS00020 (LJFMMFNO_00004) | - | 3045..3407 (+) | 363 | WP_172453717.1 | helix-turn-helix domain-containing protein | - |
| I2432_RS00025 (LJFMMFNO_00005) | ychF | 3491..4606 (+) | 1116 | WP_206158854.1 | redox-regulated ATPase YchF | - |
| I2432_RS00030 (LJFMMFNO_00006) | pth | 4765..5334 (+) | 570 | WP_043031693.1 | aminoacyl-tRNA hydrolase | - |
| I2432_RS00035 (LJFMMFNO_00007) | mfd | 5337..8831 (+) | 3495 | WP_206158855.1 | transcription-repair coupling factor | - |
| I2432_RS00040 (LJFMMFNO_00008) | - | 8800..10311 (+) | 1512 | WP_115251456.1 | oligosaccharide flippase family protein | - |
| I2432_RS00045 (LJFMMFNO_00009) | - | 10342..10614 (+) | 273 | WP_043053535.1 | RNA-binding S4 domain-containing protein | - |
| I2432_RS00050 (LJFMMFNO_00010) | - | 10601..10972 (+) | 372 | WP_012677181.1 | septum formation initiator family protein | - |
| I2432_RS10380 | - | 10982..11101 (+) | 120 | WP_012677182.1 | SP_0009 family protein | - |
| I2432_RS00055 (LJFMMFNO_00011) | - | 11114..12400 (+) | 1287 | WP_206158856.1 | serine hydrolase | - |
| I2432_RS00060 (LJFMMFNO_00012) | tilS | 12397..13680 (+) | 1284 | WP_206158857.1 | tRNA lysidine(34) synthetase TilS | - |
| I2432_RS00065 (LJFMMFNO_00013) | hpt | 13685..14227 (+) | 543 | WP_012514693.1 | hypoxanthine phosphoribosyltransferase | - |
| I2432_RS00070 (LJFMMFNO_00014) | ftsH | 14249..16222 (+) | 1974 | WP_206158858.1 | ATP-dependent zinc metalloprotease FtsH | - |
| I2432_RS00075 (LJFMMFNO_00015) | - | 16381..17775 (+) | 1395 | WP_165627774.1 | amino acid permease | - |
| I2432_RS00185 (LJFMMFNO_00037) | mreC | 24634..25485 (+) | 852 | WP_249093259.1 | rod shape-determining protein MreC | - |
| I2432_RS00190 (LJFMMFNO_00038) | mreD | 25488..25991 (+) | 504 | WP_012514697.1 | rod shape-determining protein MreD | - |
| I2432_RS00195 (LJFMMFNO_00039) | - | 26087..27265 (+) | 1179 | WP_165628003.1 | CHAP domain-containing protein | - |
| I2432_RS00200 (LJFMMFNO_00040) | - | 27370..28332 (+) | 963 | WP_021320231.1 | ribose-phosphate diphosphokinase | - |
| I2432_RS00205 (LJFMMFNO_00041) | recO | 28691..29461 (+) | 771 | WP_206158860.1 | DNA repair protein RecO | - |
| I2432_RS00210 (LJFMMFNO_00042) | plsX | 29577..30584 (+) | 1008 | WP_206158861.1 | phosphate acyltransferase PlsX | - |
| I2432_RS00215 (LJFMMFNO_00043) | - | 30577..30825 (+) | 249 | WP_206158862.1 | phosphopantetheine-binding protein | - |
| I2432_RS00220 (LJFMMFNO_00044) | purC | 30973..31683 (+) | 711 | WP_206158863.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| I2432_RS00225 (LJFMMFNO_00045) | - | 31862..35602 (+) | 3741 | WP_206158864.1 | phosphoribosylformylglycinamidine synthase | - |
| I2432_RS00230 (LJFMMFNO_00046) | purF | 35721..37178 (+) | 1458 | WP_206158865.1 | amidophosphoribosyltransferase | - |
| I2432_RS00235 (LJFMMFNO_00047) | purM | 37235..38257 (+) | 1023 | WP_206158866.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| I2432_RS00240 (LJFMMFNO_00048) | purN | 38254..38811 (+) | 558 | WP_012678772.1 | phosphoribosylglycinamide formyltransferase | - |
| I2432_RS00245 (LJFMMFNO_00049) | purH | 38958..40505 (+) | 1548 | WP_043038324.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| I2432_RS00250 (LJFMMFNO_00050) | - | 40684..41943 (-) | 1260 | WP_014622390.1 | ISL3-like element ISSeq1 family transposase | - |
| I2432_RS00255 (LJFMMFNO_00051) | - | 42306..43460 (-) | 1155 | WP_206158867.1 | CHAP domain-containing protein | - |
| I2432_RS00260 (LJFMMFNO_00052) | purD | 43816..45114 (+) | 1299 | WP_206158868.1 | phosphoribosylamine--glycine ligase | - |
| I2432_RS00265 (LJFMMFNO_00053) | purE | 45306..45794 (+) | 489 | WP_206158869.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| I2432_RS00270 (LJFMMFNO_00054) | purK | 45781..46872 (+) | 1092 | WP_206158870.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| I2432_RS00275 (LJFMMFNO_00055) | - | 46882..47106 (+) | 225 | WP_012514713.1 | hypothetical protein | - |
| I2432_RS10445 | - | 47131..47202 (+) | 72 | Protein_35 | hypothetical protein | - |
| I2432_RS00280 (LJFMMFNO_00056) | purB | 47560..48852 (+) | 1293 | WP_206158871.1 | adenylosuccinate lyase | - |
| I2432_RS00285 (LJFMMFNO_00057) | comR | 49149..50063 (+) | 915 | WP_115251528.1 | XRE family transcriptional regulator | Regulator |
| I2432_RS00295 (LJFMMFNO_00059) | ruvB | 50278..51279 (+) | 1002 | WP_111677625.1 | Holliday junction branch migration DNA helicase RuvB | - |
| I2432_RS00300 (LJFMMFNO_00060) | - | 51572..52030 (+) | 459 | WP_164336754.1 | low molecular weight protein-tyrosine-phosphatase | - |
| I2432_RS00305 (LJFMMFNO_00061) | - | 52036..52437 (+) | 402 | WP_164336752.1 | MORN repeat-containing protein | - |
| I2432_RS00310 (LJFMMFNO_00062) | - | 52434..54215 (+) | 1782 | WP_206158872.1 | acyltransferase family protein | - |
| I2432_RS00315 (LJFMMFNO_00063) | adhE | 54636..57278 (+) | 2643 | WP_164336748.1 | bifunctional acetaldehyde-CoA/alcohol dehydrogenase | - |
| I2432_RS00320 (LJFMMFNO_00064) | - | 57773..58825 (+) | 1053 | WP_012514721.1 | zinc-dependent alcohol dehydrogenase family protein | - |
| I2432_RS00325 (LJFMMFNO_00065) | adhP | 59028..60044 (+) | 1017 | WP_012514722.1 | alcohol dehydrogenase AdhP | - |
| I2432_RS00330 (LJFMMFNO_00066) | - | 60745..62337 (+) | 1593 | WP_206158873.1 | ABC transporter ATP-binding protein | - |
| I2432_RS00335 (LJFMMFNO_00068) | - | 62508..62963 (+) | 456 | WP_249093262.1 | hypothetical protein | - |
| I2432_RS00340 (LJFMMFNO_00069) | - | 62947..63810 (-) | 864 | WP_037582370.1 | Rgg/GadR/MutR family transcriptional regulator | - |
| I2432_RS00345 (LJFMMFNO_00070) | - | 64456..64722 (+) | 267 | WP_111677630.1 | hypothetical protein | - |
| I2432_RS00350 (LJFMMFNO_00071) | thrC | 64912..66396 (+) | 1485 | WP_206158874.1 | threonine synthase | - |
| I2432_RS00355 (LJFMMFNO_00072) | - | 66436..67737 (+) | 1302 | WP_206158875.1 | MATE family efflux transporter | - |
| I2432_RS00360 (LJFMMFNO_00073) | - | 67940..68893 (-) | 954 | WP_206158876.1 | IS30 family transposase | - |
Sequence
Protein
Download Length: 304 a.a. Molecular weight: 35865.36 Da Isoelectric Point: 4.4139
>NTDB_id=506276 I2432_RS00285 WP_115251528.1 49149..50063(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ13]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVIFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDVEMAEKCYDKACLFAQLTGDQYLEKKLREEWDKDIKQYQ
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVIFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDVEMAEKCYDKACLFAQLTGDQYLEKKLREEWDKDIKQYQ
Nucleotide
Download Length: 915 bp
>NTDB_id=506276 I2432_RS00285 WP_115251528.1 49149..50063(+) (comR) [Streptococcus equi subsp. zooepidemicus strain SEZ13]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGATTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCGAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACGTAGA
AATGGCAGAAAAATGTTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTAAGAG
AAGAATGGGATAAAGATATAAAACAATATCAATAG
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGATTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCGAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACGTAGA
AATGGCAGAAAAATGTTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTAAGAG
AAGAATGGGATAAAGATATAAAACAATATCAATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus pyogenes MGAS8232 |
75.248 |
99.671 |
0.75 |
| comR | Streptococcus pyogenes MGAS315 |
54.817 |
99.013 |
0.543 |
| comR | Streptococcus infantarius subsp. infantarius ATCC BAA-102 |
52.069 |
95.395 |
0.497 |
| comR | Streptococcus mutans UA159 |
48.495 |
98.355 |
0.477 |
| comR | Streptococcus suis P1/7 |
38.591 |
98.026 |
0.378 |
| comR | Streptococcus suis 05ZYH33 |
38.644 |
97.039 |
0.375 |
| comR | Streptococcus suis D9 |
37.037 |
97.697 |
0.362 |