Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR1   Type   Regulator
Locus tag   I6L86_RS00630 Genome accession   NZ_CP077259
Coordinates   119233..119517 (-) Length   94 a.a.
NCBI ID   WP_158077646.1    Uniprot ID   -
Organism   Streptococcus mitis strain FDAARGOS 1456     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Genomic Context

Location: 114233..124517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L86_RS00605 (I6L86_00605) thiE 114843..115472 (-) 630 WP_000468570.1 thiamine phosphate synthase -
  I6L86_RS00610 (I6L86_00610) thiM 115462..116256 (-) 795 WP_000202461.1 hydroxyethylthiazole kinase -
  I6L86_RS00615 (I6L86_00615) - 116491..117159 (-) 669 WP_000449832.1 TenA family protein -
  I6L86_RS00620 (I6L86_00620) lctO 117612..118748 (-) 1137 WP_000120723.1 L-lactate oxidase -
  I6L86_RS00625 (I6L86_00625) comR/comR1 118908..119090 (-) 183 WP_002877065.1 hypothetical protein Regulator
  I6L86_RS00630 (I6L86_00630) comR/comR1 119233..119517 (-) 285 WP_158077646.1 hypothetical protein Regulator
  I6L86_RS00635 (I6L86_00635) - 119849..120409 (-) 561 WP_000111604.1 TetR/AcrR family transcriptional regulator -
  I6L86_RS00640 (I6L86_00640) - 120663..121286 (+) 624 WP_000483067.1 cysteine hydrolase -
  I6L86_RS00645 (I6L86_00645) pyrE 121337..121969 (-) 633 WP_000170898.1 orotate phosphoribosyltransferase -
  I6L86_RS00650 (I6L86_00650) pyrF 122003..122704 (-) 702 WP_001206736.1 orotidine-5'-phosphate decarboxylase -
  I6L86_RS00655 (I6L86_00655) - 122937..124190 (-) 1254 WP_000031175.1 cell division protein FtsQ/DivIB -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 11125.73 Da        Isoelectric Point: 4.1207

>NTDB_id=505965 I6L86_RS00630 WP_158077646.1 119233..119517(-) (comR/comR1) [Streptococcus mitis strain FDAARGOS 1456]
MVYGDSKRITEKLTLIEEVYNCYGDILPEEELLSLDLIERILGLIRTGTGSFAEDIFDDYFKQVTLKQVYTFNDLLLIDY
FAMQCQDLIYRREH

Nucleotide


Download         Length: 285 bp        

>NTDB_id=505965 I6L86_RS00630 WP_158077646.1 119233..119517(-) (comR/comR1) [Streptococcus mitis strain FDAARGOS 1456]
ATAGTATATGGAGATTCCAAGCGTATTACGGAAAAACTAACTTTAATTGAGGAAGTTTATAATTGTTACGGTGACATCCT
TCCTGAAGAAGAGTTGCTGAGTCTAGACTTGATTGAAAGAATATTAGGCTTGATAAGAACAGGGACAGGTAGTTTCGCTG
AAGATATTTTTGATGATTATTTTAAGCAAGTAACACTAAAGCAAGTTTACACATTCAATGATTTACTATTAATTGATTAT
TTTGCTATGCAATGTCAAGACTTGATTTATAGAAGAGAGCATTAG

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(2-83)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

49.412

90.426

0.447
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

47.674

91.489

0.436
  comR Streptococcus thermophilus LMG 18311

50

85.106

0.426
  comR Streptococcus thermophilus LMD-9

50

85.106

0.426
  comR Streptococcus salivarius strain HSISS4

46.25

85.106

0.394
  comR Streptococcus salivarius SK126

45

85.106

0.383