Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   I6L85_RS00390 Genome accession   NZ_CP077248
Coordinates   56300..58453 (+) Length   717 a.a.
NCBI ID   WP_111724245.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 51300..63453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS00370 (I6L85_00370) - 51623..53062 (+) 1440 WP_111724323.1 phage/plasmid primase, P4 family -
  I6L85_RS00375 (I6L85_00375) - 53427..53951 (+) 525 WP_111724248.1 hypothetical protein -
  I6L85_RS00380 (I6L85_00380) - 54024..54527 (+) 504 WP_111724247.1 hypothetical protein -
  I6L85_RS00385 (I6L85_00385) - 55389..55598 (+) 210 WP_111724246.1 hypothetical protein -
  I6L85_RS00390 (I6L85_00390) comA 56300..58453 (+) 2154 WP_111724245.1 peptide cleavage/export ABC transporter ComA Regulator
  I6L85_RS00395 (I6L85_00395) comB 58463..59821 (+) 1359 WP_111724244.1 competence pheromone export protein ComB Regulator
  I6L85_RS00400 (I6L85_00400) lytF 59940..61589 (-) 1650 WP_111724243.1 GBS Bsp-like repeat-containing protein Regulator
  I6L85_RS00405 (I6L85_00405) purD 61834..63093 (+) 1260 WP_111724242.1 phosphoribosylamine--glycine ligase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80754.75 Da        Isoelectric Point: 7.0816

>NTDB_id=505857 I6L85_RS00390 WP_111724245.1 56300..58453(+) (comA) [Streptococcus gordonii strain FDAARGOS 1455]
MKFRKRHYRAQVDTRDCGVAALAMVFGYYGSYFSLATLREKAKTTNDGTTALGLVKVAEGLNFETRAFKADMGIFDLEYV
SYPFIVHVLKEGKLLHYYVVTGQDKHTIHIADPDPQVKMTKISRERFEQEWTGITIFLAPSPAYKPSQEKKNGLLDFIPL
LIKQKGLITNIVLATLLVTVINIVGSYYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEIVSRFTDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYAL
IIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVTYLKKSFAYGRSESLQKVLKAAARL
ILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVQSEFEEEKLIKDLSHF
QADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYAPNHGDICLGGVNLNQLDKQALRQYI
NYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIIDNLMALDKTIIFIAHRLTIAERSEQVVVLDQGRIVESGSHKELIEREGFYHHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=505857 I6L85_RS00390 WP_111724245.1 56300..58453(+) (comA) [Streptococcus gordonii strain FDAARGOS 1455]
ATGAAATTTAGGAAACGGCATTACAGAGCGCAAGTTGATACTAGGGATTGCGGTGTGGCAGCTCTGGCTATGGTTTTTGG
TTATTATGGATCGTATTTTTCCTTAGCTACACTGCGAGAAAAGGCAAAAACTACCAATGATGGCACAACTGCTTTGGGTT
TGGTAAAAGTTGCTGAGGGTCTAAATTTTGAGACAAGGGCTTTTAAAGCTGATATGGGAATCTTTGATCTGGAATATGTA
TCTTATCCTTTCATCGTTCATGTACTTAAGGAAGGGAAGCTCCTGCATTATTATGTTGTGACGGGACAAGATAAACACAC
GATTCATATTGCAGACCCAGACCCTCAAGTTAAGATGACAAAGATTTCGCGAGAGCGTTTTGAACAGGAGTGGACAGGAA
TTACCATTTTCCTAGCTCCTAGTCCAGCCTATAAGCCTAGTCAGGAAAAGAAGAATGGGCTTTTGGACTTCATTCCCTTA
TTGATCAAGCAAAAGGGGTTGATTACTAATATTGTGCTTGCAACTTTGCTGGTAACAGTGATTAATATTGTTGGATCTTA
CTACCTTCAGTCGATTATTGATACTTATGTGCCTGATCATATGAAAACGACGCTGGGTATGATTTCTATCGGCTTGATTA
TTGTCTATATTTTGCAGCAATTCTTGTCTTATGCCCAAGAATATTTGCTTTTGGTTTTAGGGCAGCGCCTATCGATTGAT
GTGATCTTATCCTATATTAAGCATGTTTTTCAGCTACCTATGTCATTTTTTGCGACAAGGCGGACAGGAGAAATCGTCTC
TCGTTTTACAGATGCCAATAGAATTATTGATGCTTTGGCCAGTACAATCTTGTCTATTTTCTTGGATGTATCGATTGTGT
CGATCATTGCGATTGTTCTTTTTTCACAAAATAGCAGTCTTTTCTTTTTGACCTTGTTAGGAATCCCAGTTTACGCTCTC
ATTATTTTTCTTTTTATGAAGCCTTTTGAAAAGATGAATCATGAGACGATGGAAGCAAATAGTTTGTTGTCGTCTTCCAT
CATTGAAGATATCAATGGGATTGAAACCATCAAGTCTTTGACCAGCGAAAAACAACGTTATCAGAAGATTGATAAGGAAT
TTGTGACTTATCTGAAAAAGTCTTTTGCTTACGGGCGTTCTGAGAGCCTACAAAAAGTCTTGAAAGCAGCAGCTCGTTTG
ATTTTAAACGTCTTGATTTTATGGCTAGGAGCTACACTTGTCATGGATCAAAAAATCAGCCTTGGTCAGCTCATTACTTA
TAACACACTTCTAGTCTACTTTACTAATCCTTTAGAAAATATTATCAATCTGCAAACGAAGTTACAGTCTGCACGAGTGG
CCAATGAGCGTCTCAATGAGGTCTATTTAGTCCAGTCTGAATTTGAAGAAGAGAAGCTTATTAAAGACTTGAGCCACTTT
CAGGCTGACATCGATTTTCGTGGAGTCAGCTATAAATATGGCTATGGGGCCAATGTATTATCAGAAATTGACTTGCATAT
TCCTGCTGGAAGTAAGACAAGCTTTGTTGGTGTATCCGGTTCAGGAAAAACAACCTTGGCCAAGATGATGGTGCATTTCT
ACGCTCCGAATCATGGGGATATTTGTTTGGGAGGAGTCAACCTCAATCAGCTGGATAAGCAGGCACTGCGCCAATATATC
AACTATCTTCCCCAGCAACCGTATGTTTTTAATGGAACTATTTTGGAAAATTTACTCTTAGGTGCGCGTGAAGGTACGAC
TCAAGAAGATATTCTGCGGGCGGTAGAATTGGCAGAAATTAGGTCGGATATTGAGCGGATGCCTCTCAATTATCAGACAG
AGCTGTCTGCAGATGGAGCAGGAATCTCGGGTGGTCAACGTCAGCGTATTGCTTTAGCAAGGGCTCTCTTGACAGATGCG
CCAGTGCTTATCTTAGATGAAGCAACGAGTAGTCTGGATATTCTAACAGAGAAGCGGATCATTGATAATCTGATGGCGCT
TGATAAGACGATTATTTTCATCGCGCATCGTTTGACTATTGCGGAACGTTCGGAGCAGGTGGTCGTTTTGGATCAAGGTA
GGATTGTCGAGAGTGGAAGTCATAAGGAGCTGATCGAAAGAGAAGGCTTTTACCACCATTTGGTCAATAGTTAG

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(500-650)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(170-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

98.187

100

0.982
  comA Streptococcus pneumoniae Rx1

80.893

100

0.809
  comA Streptococcus pneumoniae D39

80.893

100

0.809
  comA Streptococcus pneumoniae R6

80.893

100

0.809
  comA Streptococcus mitis NCTC 12261

80.753

100

0.808
  comA Streptococcus mitis SK321

80.614

100

0.806
  comA Streptococcus pneumoniae TIGR4

80.474

100

0.805
  comA/nlmT Streptococcus mutans UA159

64.714

100

0.647